Pharmacological evidences for the blood pressure lowering and cardiovascular inhibitory actions of the essential oil of <i>Thymus serrulatus</i> hochst. Ex benth. [PDF]
Front PharmacolRehman NU +6 more
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Guava Leaf Extract as a Sustainable Preservative Alternative in Semi-Solid Pharmaceuticals: Efficacy and Stability Assessment. [PDF]
Antibiotics (Basel)Imtara H +5 more
europepmc +1 more source
Terrestrial planetary plants: Essential preparations for interstellar migration [PDF]
Zhan, Jiasui
openalex
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Medicinal Plants in Food Supplements for Gastrointestinal Disorders: Critical Assessment of Health Claims on Gastric Acid Regulation. [PDF]
NutrientsTeterovska R +3 more
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Application of response surface methodology for obtaining fermented extract of <i>Sanguisorba officinalis</i> L. herb with high antioxidant activity, polyphenols, and lactic acid content: analysis of the content and skin permeation of selected phenolic acids. [PDF]
RSC AdvMuzykiewicz-Szymańska A +4 more
europepmc +1 more source