The SNF1-type serine-threonine protein kinase SAPK4 regulates stress-responsive gene expression in rice [PDF]
Diedhiou CJ, Popova OV, Dietz K-J, Golldack D. The SNF1-type serine-threonine protein kinase SAPK4 regulates stress-responsive gene expression in rice. BMC PLANT BIOLOGY.
Popova Olga V +7 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The potato mop-top virus TGB2 protein and viral RNA associate with chloroplasts and viral infection induces inclusions in the plastids [PDF]
The potato mop-top virus (PMTV) triple gene block 2 (TGB2) movement proteins fused to monomeric red fluorescent protein (mRFP-TGB2) was expressed under the control of the PMTV subgenomic promoter from a PMTV vector.
Roberts, Alison G. +21 more
core +1 more source
CD5L associates with IgM via the J chain
CD5 antigen-like (CD5L), also known as Spα or AIM (Apoptosis inhibitor of macrophage), emerges as an integral component of serum immunoglobulin M (IgM). However, the molecular mechanism underlying the interaction between IgM and CD5L has remained elusive.
Yuxin Wang +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An Outlook on the Localisation and Structure-Function Relationships of R Proteins in Solanum [PDF]
The co-evolution of plants and plant-pathogens shaped a multi-layered defence system in plants, in which Resistance proteins (R proteins) play a significant role.
Goverse, A. +11 more
core +1 more source
Architecture and activation of human muscle phosphorylase kinase
The study of phosphorylase kinase (PhK)-regulated glycogen metabolism has contributed to the fundamental understanding of protein phosphorylation; however, the molecular mechanism of PhK remains poorly understood. Here we present the high-resolution cryo-
Xiaoke Yang +4 more
doaj +1 more source
A minus-end directed kinesin motor directs gravitropism in Physcomitrella patens
Gravitropism is the process by which plants perceive and respond to gravity. Here the authors identify a minus-end-directed kinesin required for gravity-triggered actin filament rearrangement and negative gravitropic response in the moss Physcomitrella ...
Yufan Li +11 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A study of the Microtubule associated protein family, MAP65, in Arabidopsis [PDF]
Microtubules (MTs) play a key role in cell division and morphogenesis. Plant cells form four distinct MT arrays through the cell cycle; the interphase cortical array, the preprophase band, the spindle and the phragmoplast.
Kaloriti, Despina
core

