Results 71 to 80 of about 1,383,408 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

C. elegans enteric motor neurons fire synchronized action potentials underlying the defecation motor program

Nature Communications, 2022
Most neurons in the nematode C. elegans communicate in an analog manner. Here, the authors demonstrate that enteric motor neurons can fire all-or-none action potentials, and that this digital communication is important for defecation.
Jingyuan Jiang, Yifan Su, Ruilin Zhang, Haiwen Li, Louis Tao, Qiang Liu   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A transcriptional activator effector of Ustilago maydis regulates hyperplasia in maize during pathogen-induced tumor formation

Nature Communications, 2023
Ustilago maydis causes common smut in maize, which is characterized by tumor formation in aerial parts of maize. Tumors result from the de novo cell division of highly developed bundle sheath and subsequent cell enlargement.
Weiliang Zuo, Jasper R. L. Depotter, Sara Christina Stolze, Hirofumi Nakagami, Gunther Doehlemann   +4 more
doaj   +1 more source

Improved digestibility and growth in selected families of rainbow trout (Oncorhynchus mykiss) [PDF]

, 2008
Protein is the most expensive single component in fish feed and the quality of the dietary protein is decisive for the productivity of fish farming. When fish meal is partly replaced by plant protein in feed for organic fish it is especially important ...
Jokumsen, Alfred, Skøtt Rasmussen, Richard   +1 more
core  

Eating Pattern Response to a Low-Fat Diet Intervention and Cardiovascular Outcomes in Normotensive Women: The Women's Health Initiative. [PDF]

, 2020
BackgroundWomen without cardiovascular disease (CVD) or hypertension at baseline assigned to intervention in the Women's Health Initiative Dietary Modification (DM) trial experienced 30% lower risk of coronary heart disease (CHD), whereas results in ...
Allison, Matthew A, Aragaki, Aaron K, Howard, Barbara V, Isasi, Carmen R, Manson, JoAnn E, Mossavar-Rahmani, Yasmin, Neuhouser, Marian L, Prentice, Ross L, Thomson, Cynthia A, Van Horn, Linda, Vitolin, Mara Z, Wallace, Robert B, WHI Investigators   +12 more
core   +1 more source

Toxic proteins in plants

Phytochemistry, 2015
Plants have evolved to synthesize a variety of noxious compounds to cope with unfavorable circumstances, among which a large group of toxic proteins that play a critical role in plant defense against predators and microbes. Up to now, a wide range of harmful proteins have been discovered in different plants, including lectins, ribosome-inactivating ...
Dang, Liuyi, Van Damme, Els J.M.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

ABI4 Mediates Antagonistic Effects of Abscisic Acid and Gibberellins at Transcript and Protein Levels [PDF]

, 2016
Abscisic acid (ABA) and gibberellins (GA) are plant hormones which antagonistically mediate numerous physiological processes, and their optimal balance is essential for normal plant development.
Cao, XiaoFeng, Chen, Qian, Li, Yanli, Liu, Chunyan, Liu, Ruijun, SERINO, Giovanna, Shu, Kai, Tang, Sanyuan, Wang, Pengfei, Wang, Shengfu, Wu, Yaorong, Xie, Qi, Yang, Wenyu, Zhang, Huawei   +13 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source