Results 171 to 180 of about 9,919,201 (390)

Protein Nutrition: Understanding Structure, Digestibility, and Bioavailability for Optimal Health

open access: yesFoods
This review discusses different protein sources and their role in human nutrition, focusing on their structure, digestibility, and bioavailability.
Nneka Ajomiwe   +5 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Probiotics application in aquaculture: its potential effects, current status in China and future prospects

open access: yesFrontiers in Marine Science
Today’s increasing demand for aquaculture production is accompanied by various challenges such as diseases, broodstock improvement, domestication, development of suitable pellets and feeding methods, hatchery technology, and water quality management ...
Silvana Rahayu   +31 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Protein Kinases and Plant Pores

open access: yesPLoS Biology, 2006
When water is scarce, plants synthesize a hormone that facilitates conservation by closing stomatal pores on their leaves. Each pore is surrounded by a pair of guard cells that control stomatal aperture in response to various stimuli, including the drought-triggered hormone called abscisic acid (ABA).
openaire   +5 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Agro-Industrial Plant Proteins in Electrospun Materials for Biomedical Application. [PDF]

open access: yesPolymers (Basel), 2023
Zdraveva E   +5 more
europepmc   +1 more source

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