Results 151 to 160 of about 198,406 (257)

Protocol for characterizing strigolactones released by plant roots. [PDF]

STAR Protoc, 2022
Wang JY, Chen GE, Jamil M, Braguy J, Sioud S, Liew KX, Balakrishna A, Al-Babili S.   +7 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Rooted Soil Shear Apparatus: A low-cost, direct shear apparatus for measuring the influence of plant roots on soil shear strength. [PDF]

HardwareX
Sorrentino G, Otim GI, Zhelezova A, Rocchi I.   +3 more
europepmc   +1 more source

Radial Oxygen Loss from Plant Roots-Methods. [PDF]

Plants (Basel), 2021
Jiménez JC, Pellegrini E, Pedersen O, Nakazono M.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Innovative Hydroponic Culture of <i>Alkanna tinctoria</i> (L.) Tausch: An Approach Towards Sustainable Extraction Process from Plant Roots. [PDF]

Plants (Basel)
Bossard E, Cartabia A, Lalaymia I, Tsafantakis N, Aligiannis N, Chinou I, Declerck S, Fokialakis N.   +7 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Abscisic acid signaling gates salt-induced responses of plant roots. [PDF]

Proc Natl Acad Sci U S A
Lamers J, Zhang Y, van Zelm E, Leong CK, Meyer AJ, de Zeeuw T, Verstappen F, Veen M, Deolu-Ajayi AO, Gommers CMM, Testerink C.   +10 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Mechanical mechanism of soil consolidation by plant roots in loess area of northern Shaanxi. [PDF]

Sci Rep
Xu R, He Y, Cheng H, Deng J, Wei H, Wang G, Li X, Yang W.   +7 more
europepmc   +1 more source