Results 181 to 190 of about 3,048,042 (302)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Evolutionary trajectory of the NPF6.3(NRT1.1/CHL1)-centered nitrate signaling regulatory network in plant roots. [PDF]

BMC Plant Biol
Zhao R, Wang J, Yi X, Wang J, Xu P, Duan X, Wu H, Jiao Y.   +7 more
europepmc   +1 more source

A blast from the past: Understanding stem cell specification in plant roots using laser ablation. [PDF]

Quant Plant Biol, 2023
Smet W, Blilou I.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Properties of Human Gastric Lipase Produced by Plant Roots. [PDF]

Life (Basel), 2022
Guerineau F.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Pullout Behaviour and Influencing Mechanisms of Desert Plant Roots in Clayey Sand During Thawing. [PDF]

Plants (Basel)
Yang X, Li Q, Yu S, Feng P, Zhang M, Chen W, Yang G.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Light is sufficient to compensate for random positioning machine-simulated microgravity in plant roots. [PDF]

NPJ Microgravity
David R, Situmorang A, Tran NN, Maythwe T, Hessel V, Brewer PB.   +5 more
europepmc   +1 more source

A mechano-sensing mechanism for waving in plant roots. [PDF]

Sci Rep, 2022
Zhang Z, van Ophem D, Chelakkot R, Lazarovitch N, Regev I.   +4 more
europepmc   +1 more source