Results 191 to 200 of about 881,012 (303)

A mechano-sensing mechanism for waving in plant roots. [PDF]

open access: yesSci Rep, 2022
Zhang Z   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Needle in a Haystack: Culturing Plant-Beneficial Helotiales Lineages From Plant Roots. [PDF]

open access: yesEnviron Microbiol
Bruyant P   +4 more
europepmc   +1 more source

Iterative image segmentation of plant roots for high-throughput phenotyping. [PDF]

open access: yesSci Rep, 2022
Seidenthal K   +4 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Opposing regulation of L-theanine biosynthesis by CsWRKY65 and CsWRKY69 in tea plant roots. [PDF]

open access: yesHortic Res
Liu P   +8 more
europepmc   +1 more source

Protocol for characterizing strigolactones released by plant roots. [PDF]

open access: yesSTAR Protoc, 2022
Wang JY   +7 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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