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Plant sterols and atherosclerosis

Current Opinion in Lipidology, 2013
Plant sterols as ingredients to functional foods are recommended for lowering LDL cholesterol. However, there is an ongoing discussion whether the use of plant sterols is safe.Genetic analyses showed that common variants of the ATP binding cassette transporter G8 (ABCG8) and ABO genes are associated with elevated circulating plant sterols and higher ...
Günther, Silbernagel   +3 more
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Cholesterol-lowering effect of plant sterols

Current Atherosclerosis Reports, 2008
Plant sterols are plant components that have a chemical structure similar to cholesterol except for the addition of an extra methyl or ethyl group; however, plant sterol absorption in humans is considerably less than that of cholesterol. In fact, plant sterols reduce cholesterol absorption and thus reduce circulating levels of cholesterol.
Suhad S, AbuMweis, Peter J H, Jones
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Metabolism of plant sterols by nematodes

Lipids, 1991
AbstractParasitic nematodes do not biosynthesize sterolsde novo and therefore possess a nutritional requirement for sterol, which must be obtained from their hosts. Consequently, the metabolism of phytosterols by plant‐parasitic nematodes is an important process with potential for selective exploitation.
D J, Chitwood, W R, Lusby
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Dietary Plant Sterols and Cholesterol Metabolism

Nutrition Reviews, 2007
Plant sterols, naturally occurring in foods of plant origin, reduce cholesterol absorption. Experimental studies show plant sterols to be an important part of the serum-cholesterol lowering effect of certain diets and dietary components. Epidemiological data show that individuals with higher intakes of plant sterols from their habitual diets have lower
Lars H, Ellegård   +3 more
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Plant Sterol Biosynthesis: Identification and Characterization of Higher Plant Δ7-Sterol C5(6)-Desaturase

Archives of Biochemistry and Biophysics, 1996
Microsomes obtained from maize seedlings catalyzed the introduction of the delta5-bond into delta7-sterols to yield the corresponding delta 5,7-sterols. Enzymatic bioassay conditions have been developed for the first time for delta 7-sterol C5(6)-desaturase in photosynthetic organisms.
M, Taton, A, Rahier
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Plant Sterol Diversity in Pollen from Angiosperms

Lipids, 2015
AbstractHere we have examined the composition of free sterols and steryl esters of pollen from selected angiosperm species, as a first step towards a comprehensive analysis of sterol biogenesis in the male gametophyte. We detected four major sterol structural groups: cycloartenol derivatives bearing a 9β,19‐cyclopropyl group, sterols with a double bond
Villette, C.   +3 more
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Plant Sterols and Stanols

2005
The expanding market of 'functional foods' containing plant sterols and stanols has focused interest on their cholesterol-lowering effects as well on possible adverse effects. Trials of cholesterol lowering demonstrate that intake of 2 g/day of plant sterols and stanols reduces serum low-density lipoprotein (LDL) cholesterol concentrations by ...
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Action of Plant Sterol Intervention on Sterol Kinetics in Hypercholesterolemic Men with High versus Low Basal Circulatory Plant Sterol Concentrations

Journal of the American College of Nutrition, 2011
The relationship between plant sterol (PS) absorption and circulatory concentrations with cholesterol absorption and biosynthesis during PS consumption has yet to be clearly elucidated in humans. It is therefore essential to examine campesterol, β-sitosterol, and cholesterol absorption and cholesterol fractional synthesis rate (FSR) following PS ...
Hai L, Zhao   +6 more
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Plant sterols and blood lipid levels

Current Opinion in Clinical Nutrition and Metabolic Care, 2002
Plant sterols have recently been recommended by the National Cholesterol Education Panel for use with the more traditional approaches of limiting saturated fat and cholesterol intakes, maintaining a healthy body weight and engaging in regular exercise, as a non-pharmacological approach to reduce low-density lipoprotein cholesterol levels.
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Cholesterol-lowering action of plant sterols

Current Atherosclerosis Reports, 1999
Plant sterols have an extended history of use as cholesterol-lowering agents. Until the 1970s, the principal interest in plant sterols lay in effects of sitosterol, but over the past decade interest has reemerged in using plant sterols in functional foods.
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