Results 1 to 10 of about 29,656 (233)
β‐sitosterol Alleviates Pulmonary Arterial Hypertension in Rats With Involvement of the VEGF/PI3K/AKT Signaling Pathway [PDF]
Pulm CircABSTRACT Pulmonary arterial hypertension (PAH) is a progressive and lethal disorder with limited therapeutic options. β‐sitosterol, a plant compound, has shown potential in managing PAH, but its protective mechanisms remain unclear. We evaluated the protective effects of β‐sitosterol against monocrotaline (MCT)‐induced PAH in rats and explored the ...
Wu X, Gong C, Zeng Z.
europepmc +2 more sources
Integrated Experimental, Chemometric, and In Silico Analyses of Larvicidal Supercritical Extracts From Myrtaceae Species Against Aedes aegypti. [PDF]
Chem BiodiversThe cross‐validated regression tree showed modest predictive performance. Mortality was not significantly associated with the first two PCA axes. Molecular modeling generated testable ligand–target hypotheses. Psidium cattleianum had lower LD50. The larvicidal activity of the crude extracts could not be attributed to individual constituents.
Bones UA +8 more
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Inhibition of Phytosterol Biosynthesis by Azasterols
Molecules, 2020 Inhibitors of enzymes in essential cellular pathways are potent probes to decipher intricate physiological functions of biomolecules. The analysis of Arabidopsis thaliana sterol profiles upon treatment with a series of azasterols reveals a specific in ...
Sylvain Darnet +5 more
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Metabolites, 2023 Plant sterols are molecules that are structurally similar to cholesterol and provided only as dietary sources (e.g., vegetables, fruits, nuts, cereals) since they cannot be synthesized by humans.
Panagiotis Anagnostis +3 more
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Experimental Study For The Effect of β- Sitosterol on the level of Male,s hormones [PDF]
Kirkuk Journal of Science, 2017 The effect of β-Sitosterol to the levels of male,s hormones was carried out in sera of adult male rabbit, twenty eight of local rabbite, weigh aging range between (800-1500)g.
Esraa Ali Abdul kareem +1 more
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Journal of Lipid Research, 1998 Sitosterolemia is a recessively inherited disorder characterized by abnormally increased plasma and tissue plant sterol concentrations. Patients have markedly reduced whole body cholesterol biosynthesis associated with suppressed hepatic, ileal, and ...
Akira Honda +5 more
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RESPONSE OF WHEAT PLANT (Triticum aestivum L.) TO FOLIAR APPLICATION OF SITOSTEROL AND ETHREL. [PDF]
Journal of Plant Production, 2006 Two field experiments on wheat ( Triticum aestivum L.) c.v. Gemmiza-9 were conducted to study the effect of different concentrations of sitosterol (100, 150 and 200 mg/i ) , ethrel ( 0, 100 and 150 mg/I ) and their interaction on growth ...
A . Amin,
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundWe have investigated serum levels of immunoreactive marinobufagenin (MBG) in 16‐ to 20‐week‐old spontaneously hypertensive rats (SHRs)‐A3 and in the normotensive Wistar‐Kyoto (WKY) rat strain in the absence of salt loading, and we have ...
Renata I. Dmitrieva +2 more
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Steroidal Triterpenes: Design of Substrate-Based Inhibitors of Ergosterol and Sitosterol Synthesis
Molecules, 2009 This article reviews the design and study, in our own laboratory and others, of new steroidal triterpenes with a modified lanosterol or cycloartenol frame.
Jialin Liu, William David Nes
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Plants, 2023 The prevalence of benign prostatic hyperplasia (BPH) markedly increases with age. Phytotherapeutic approaches have been developed over time owing to the adverse side effects of conventional medications such as 5-reductase inhibitors and α1-adrenergic ...
Mădălina-Georgiana Buț +6 more
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