Results 1 to 10 of about 2,628 (117)

β-Sitosterol, β-Sitosterol Glucoside, and a Mixture of β-Sitosterol and β-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice [PDF]

open access: yesJournal of Nutrition, 2004
We hypothesized that the phytosterols beta-sitosterol (BSS), beta-sitosterol glucoside (BSSG), and Moducare (MC; BSS:BSSG = 99:1) could modulate the growth of estrogen-dependent human breast cancer cells in vitro and in vivo. The present study evaluated the estrogenic and antiestrogenic effects of BSS, BSSG, and MC (0.001 to 150 micromol/L) on the ...
William Helferich   +2 more
exaly   +3 more sources

Inhibition of Phytosterol Biosynthesis by Azasterols

open access: yesMolecules, 2020
Inhibitors of enzymes in essential cellular pathways are potent probes to decipher intricate physiological functions of biomolecules. The analysis of Arabidopsis thaliana sterol profiles upon treatment with a series of azasterols reveals a specific in ...
Sylvain Darnet   +5 more
doaj   +1 more source

Could Lowering Phytosterol Absorption as Part of Lipid-Lowering Therapy Have a Beneficial Effect on Residual Risk?

open access: yesMetabolites, 2023
Plant sterols are molecules that are structurally similar to cholesterol and provided only as dietary sources (e.g., vegetables, fruits, nuts, cereals) since they cannot be synthesized by humans.
Panagiotis Anagnostis   +3 more
doaj   +1 more source

Experimental Study For The Effect of β- Sitosterol on the level of Male,s hormones [PDF]

open access: yesKirkuk Journal of Science, 2017
The effect of β-Sitosterol to the levels of male,s hormones was carried out in sera of adult male rabbit, twenty eight of local rabbite, weigh aging range between (800-1500)g.
Esraa Ali Abdul kareem   +1 more
doaj   +1 more source

Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol Δ7-reductase in liver and mononuclear leukocytes

open access: yesJournal of Lipid Research, 1998
Sitosterolemia is a recessively inherited disorder characterized by abnormally increased plasma and tissue plant sterol concentrations. Patients have markedly reduced whole body cholesterol biosynthesis associated with suppressed hepatic, ileal, and ...
Akira Honda   +5 more
doaj   +1 more source

RESPONSE OF WHEAT PLANT (Triticum aestivum L.) TO FOLIAR APPLICATION OF SITOSTEROL AND ETHREL. [PDF]

open access: yesJournal of Plant Production, 2006
Two field experiments on wheat ( Triticum aestivum L.) c.v. Gemmiza-9 were conducted to study the effect of different concentrations of sitosterol (100, 150 and 200 mg/i ) , ethrel ( 0, 100 and 150 mg/I ) and their interaction on growth ...
A . Amin,
doaj   +1 more source

Genetic Control of Serum Marinobufagenin in the Spontaneously Hypertensive Rat and the Relationship to Blood Pressure

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundWe have investigated serum levels of immunoreactive marinobufagenin (MBG) in 16‐ to 20‐week‐old spontaneously hypertensive rats (SHRs)‐A3 and in the normotensive Wistar‐Kyoto (WKY) rat strain in the absence of salt loading, and we have ...
Renata I. Dmitrieva   +2 more
doaj   +1 more source

Steroidal Triterpenes: Design of Substrate-Based Inhibitors of Ergosterol and Sitosterol Synthesis

open access: yesMolecules, 2009
This article reviews the design and study, in our own laboratory and others, of new steroidal triterpenes with a modified lanosterol or cycloartenol frame.
Jialin Liu, William David Nes
doaj   +1 more source

The Lack of Standardization and Pharmacological Effect Limits the Potential Clinical Usefulness of Phytosterols in Benign Prostatic Hyperplasia

open access: yesPlants, 2023
The prevalence of benign prostatic hyperplasia (BPH) markedly increases with age. Phytotherapeutic approaches have been developed over time owing to the adverse side effects of conventional medications such as 5-reductase inhibitors and α1-adrenergic ...
Mădălina-Georgiana Buț   +6 more
doaj   +1 more source

Effects of diet and metamorphosis upon the sterol composition of the butterfly Morpho peleides

open access: yesJournal of Lipid Research, 2006
Whole body sterol metabolism in insects has seldom been studied. We were able to design an appropriate study at a butterfly farm in Belize. We collected six larvas of butterfly (Morpho peleides), their food (leaves of Pterocarpus bayessii), and their ...
William E. Connor   +3 more
doaj   +1 more source

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