Inhibition of cholesterol absorption by the combination of dietary plant sterols and ezetimibe
Consumption of plant sterols and treatment with ezetimibe both reduce cholesterol absorption in the intestine. However, the mechanism of action differs between the two treatments, and the consequences of combination treatment are unknown.
Lily Jakulj +5 more
doaj +1 more source
Sterol content in sunflower seeds (Helianthus annuus L.) as affected by genotypes and environmental conditions [PDF]
Phytosterols play essential roles in many plant cell mechanisms. They are of industrial interest since, as part of the diet, they can reduce Low Density Lipoprotein cholesterol.
Roche, Jane, J. +20 more
core +1 more source
β-Sitosterol Inhibits The Proliferation of Endometrial Cells via Regulating Smad7-Mediated TGF-β/Smads Signaling Pathway [PDF]
Objective: To investigate the effect of β-sitosterol on endometrial cells to understand the underlying mechanism.Materials and Methods: This is a laboratory-based experimental study conducted on animals and cells.
Yi Wen +6 more
doaj +1 more source
Metabolism of β-sitosterol in man [PDF]
The metabolism of beta-sitosterol was compared to that of cholesterol in 12 patients. Sterol balance methods were supplemented by radiosterol studies, with the following results. (a) Plasma concentrations of beta-sitosterol ranged from 0.30 to 1.02 mg/100 ml plasma in patients on intakes of beta-sitosterol typical of the American diet.
G, Salen, E H, Ahrens, S M, Grundy
openaire +2 more sources
Functional analysis of candidate ABC transporter proteins for sitosterol transport [PDF]
Two ATP-binding cassette (ABC) proteins, ABCG5 and ABCG8, have recently been associated with the accumulation of dietary cholesterol in the sterol storage disease sitosterolemia.
Higgins, C F +6 more
core +2 more sources
Stinging Nettle (Urtica dioica) Roots: The Power Underground—A Review
Stinging nettle (Urtica dioica) is an herbaceous perennial plant native to Eurasia, wildly distributed throughout the temperate parts of the world. Although generally considered as a weed due to its fast growth and invasive capacity, stinging nettle is ...
Françoise Martz, Santeri Kankaanpää
doaj +1 more source
Changes in the balance of cholesterol absorption and synthesis and moderately elevated plasma plant sterols have been suggested to be atherogenic. Measuring cholestanol, lathosterol, campesterol, and sitosterol, we investigated the relationships of ...
Guenther Silbernagel +7 more
doaj +1 more source
ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile
The major pathway for the removal of cholesterol from the body is via secretion into the bile. Three members of the ATP binding cassette (ABC) family, ABCG5 (G5), ABCG8 (G8), and ABCB4 (MDR2), are required for the efficient biliary export of sterols ...
Silvia Langheim +6 more
doaj +1 more source
Elucidation of the anticancer potential and tubulin isotype-specific interactions of β-sitosterol
Beta-sitosterol (β-SITO), a phytosterol present in many edible vegetables, has been reported to possess antineoplastic properties and cancer treatment potential.
Sinjan Choudhary (617211) +4 more
core +1 more source
Quantum Chemical Treatment of ?-Sitosterol Molecule
beta-Sitosterol is used as a dietary supplement for lowering plasma cholesterol, and has atherosclerosis preventive, anti-inflammatory, antimicrobial, antipyretic, induced apoptosis, and anticancer effects.
Erkoç, Şakir +2 more
core +2 more sources

