Results 11 to 20 of about 65,671 (281)

Anti-Inflammatory and Antioxidant Properties of β-Sitosterol in Copper Sulfate-Induced Inflammation in Zebrafish (Danio rerio)

Antioxidants, 2023
β-Sitosterol, which is used extensively in pharmaceuticals, nutraceuticals, and cosmetics, has high nutritional value along with immunomodulatory and anti-inflammatory properties.
Peng Zhang, Mingyang Xue, Chen Xu
exaly   +2 more sources

An update on β-sitosterol: A potential herbal nutraceutical for diabetic management

Biomedicine and Pharmacotherapy, 2020
Phytosterols are bioactive compounds that are naturally present in plant cell membranes with chemical structure similar to the mammalian cell- derived cholesterol.
Selvaraj Jayaraman, shyamaladevi Babu
exaly   +2 more sources

Effect of β-sitosterol on the curcumin-loaded liposomes: Vesicle characteristics, physicochemical stability, in vitro release and bioavailability

Food Chemistry, 2019
In this work, the effect of β-sitosterol (Sito) on vesicle characteristics, physicochemical stability as well as the in vitro release and bioavailability of curcumin-loaded liposomes (Cur-LP) was studied.
Kedong Tai, Michael Rappolt, Yang Wei
exaly   +2 more sources

β-Sitosterol-loaded solid lipid nanoparticles ameliorate complete Freund’s adjuvant-induced arthritis in rats: involvement of NF-кB and HO-1/Nrf-2 pathway

Drug Delivery, 2020
Rheumatoid arthritis (RA), autoimmune disease that is categorized via chronic inflammation manifestation, obesity, cardiovascular risk and even enhanced the mortality and affect the 0.3 and 1% of population worldwide.
Feng Zhang, Xijing He
exaly   +2 more sources

β-Sitosterol, β-Sitosterol Glucoside, and a Mixture of β-Sitosterol and β-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice [PDF]

Journal of Nutrition, 2004
We hypothesized that the phytosterols beta-sitosterol (BSS), beta-sitosterol glucoside (BSSG), and Moducare (MC; BSS:BSSG = 99:1) could modulate the growth of estrogen-dependent human breast cancer cells in vitro and in vivo. The present study evaluated the estrogenic and antiestrogenic effects of BSS, BSSG, and MC (0.001 to 150 micromol/L) on the ...
William G Helferich
exaly   +3 more sources

β-Sitosterol as a Promising Anticancer Agent for Chemoprevention and Chemotherapy: Mechanisms of Action and Future Prospects

Advances in Nutrition, 2023
Cancer is one of the primary causes of death worldwide, and its incidence continues to increase yearly. Despite significant advances in research, the search for effective and nontoxic preventive and therapeutic agents remains greatly important. Cancer is
Haoyu Wang, Zhi Wang, Zihui Zhang, Jingchun Liu, Li Hong   +4 more
semanticscholar   +1 more source

β-sitosterol attenuates high- fat diet-induced hepatic steatosis in rats by modulating lipid metabolism, inflammation and ER stress pathway

BMC Pharmacology and Toxicology, 2023
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic hepatic disorder. The naturally occurring phytosterol; β-sitosterol has antiobesogenic and anti-diabetic properties.
Omayma A R Abo-Zaid, F. Moawed, Effet Soliman Ismail, M. Farrag   +3 more
semanticscholar   +1 more source

Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis

Neural Regeneration Research, 2023
[INLINE:1] β-Sitosterol is a type of phytosterol that occurs naturally in plants. Previous studies have shown that it has anti-oxidant, anti-hyperlipidemic, anti-inflammatory, immunomodulatory, and anti-tumor effects, but it is unknown whether β ...
Xiuling Tang, Tao Yan, Saiying Wang, Qingqing Liu, Qi Yang, Yong-qiang Zhang, Yu-jiao Li, Yumei Wu, Shui-bing Liu, Yulong Ma, Le Yang   +10 more
semanticscholar   +1 more source

β-Sitosterol blocks the LEF-1-mediated Wnt/β-catenin pathway to inhibit proliferation of human colon cancer cells.

Cellular Signalling, 2023
OBJECTIVES This study aimed to investigate the LEF-1-mediated Wnt/β-catenin pathway for its biological functions and prognostic value in colon cancer (CC).
Shengliang Gu, Fahui Liu, Xueheng Xie, Meng Ding, Fan Wang, Xiaoyan Xing, Tianbao Xiao, Xiaobo Sun   +7 more
semanticscholar   +1 more source

Inhibition of Phytosterol Biosynthesis by Azasterols

Molecules, 2020
Inhibitors of enzymes in essential cellular pathways are potent probes to decipher intricate physiological functions of biomolecules. The analysis of Arabidopsis thaliana sterol profiles upon treatment with a series of azasterols reveals a specific in ...
Sylvain Darnet, Laetitia B B Martin, Pierre Mercier, Franz Bracher, Philippe Geoffroy, Hubert Schaller   +5 more
doaj   +1 more source