Results 71 to 80 of about 2,680,264 (291)

Sitosterolemia.

Journal of Lipid Research, 1992
Sitosterolemia is a rare inherited lipid storage disease characterized chemically by the accumulation of plant sterols and 5 alpha-saturated stanols in plasma and tissues. Very low cholesterol synthesis due to a deficiency of HMG-CoA reductase associated
G Salen, S Shefer, L Nguyen, GC Ness, GS Tint, V Shore   +5 more
doaj   +1 more source

Disruption of cholesterol homeostasis by plant sterols [PDF]

Journal of Clinical Investigation, 2004
The ABC transporters ABCG5 and ABCG8 limit absorption and promote excretion of dietary plant sterols. It is not known why plant sterols are so assiduously excluded from the body. Here we show that accumulation of plant sterols in mice lacking ABCG5 and ABCG8 (G5G8-/- mice) profoundly perturbs cholesterol homeostasis in the adrenal gland.
Chendong, Yang, Liqing, Yu, Weiping, Li, Fang, Xu, Jonathan C, Cohen, Helen H, Hobbs   +5 more
openaire   +2 more sources

Plant sterols: Friend or foe in CNS disorders?

, 2015
In mammals, the central nervous system (CNS) is the most cholesterol rich organ by weight. Cholesterol metabolism is tightly regulated in the CNS and all cholesterol available is synthesized in situ.
Vanmol, J, Mulder, Maarten, Bogie, Jeroen F. J., Mulder, Monique, VANMIERLO, Tim, MAILLEUX, Jo, VANMOL, Jasmine, Bogie, Jeroen, Mailleux, J, Vanmierlo, T, Lutjohann, D, Hendriks, JJA, Hendriks, Jerome J. A., Luetjohann, Dieter   +13 more
core   +1 more source

Multi‐Omics Analyses Identify Candidate Genes Associated With Stage‐Specific Quality Formation in Mulching‐Treated Moso Bamboo Shoots

Advanced Science, EarlyView.
Organic mulching reprograms Moso bamboo shoot development, enhancing yield and nutritional quality. This multi‐omics study reveals that coordinated metabolic, transcriptional, and post‐transcriptional regulation drives stage‐specific quality formation, offering comprehensive insights into how this agricultural practice improves crop performance and ...
Bo Wang, Yanbin Wang, Chunyue Wang, Zishan Ahmad, Peixin Teng, Huijing Ni, Qiang Wei, Muthusamy Ramakrishnan   +7 more
wiley   +1 more source

POTENTIAL HEALTHCARE SAVINGS FROM PLANT STEROL ENRICHED FOODS IN CANADA [PDF]

Increased consumption of foods containing plant sterols has the potential to reduce the incidence of coronary heart disease (CHD) and thus reduce costs associated with treating that disease in a significant way.
Gyles, Collin, Jones, Peter J.H., Carlberg, Jared G.   +2 more
core  

Bacterial Geosmin Biosynthesis is Compartmentalized Inside a Two‐Component Protein Shell

Advanced Science, EarlyView.
This study reports the discovery that geosmin biosynthesis is compartmentalized inside a two‐component protein shell in many bacteria. Sequestration of geosmin synthase inside a Family 2B encapsulin nanocompartment improves geosmin yield and increases enzyme stability as compared to the free enzyme.
Asif Fazal, Cassandra A. Dutcher, Michael P. Andreas, Tobias W. Giessen   +3 more
wiley   +1 more source

Serum squalene and noncholesterol sterols before and after delivery in normal and cholestatic pregnancy

Journal of Lipid Research, 1996
Mechanisms of hyperlipidemia were studied by measurement of serum lipid concentrations and the ratios of cholesterol precursors (squalene, delta 8-cholestenol, desmosterol, and lathosterol), plant sterols (campesterol and sitosterol), and cholestanol (a ...
K Nikkilä, S Riikonen, M Lindfors, T A Miettinen   +3 more
doaj   +1 more source

Comparative Profiles of Lipophilic Nutrients and In Vitro Antioxidant Activity in Commercial Arabica and Robusta Green Coffee Beans

Journal of the American Oil Chemists' Society, EarlyView.
Integrated compositional profiling of ten commercial green coffee lots showed higher mean total phenolic content, DPPH radical‐scavenging activity, β‐carotene, and total phytosterols in Robusta‐labeled lots, whereas Arabica‐labeled lots showed higher mean total tocopherols and total measured fatty acids.
Muyny Chhom, Youngmin Choi, Jung‐Ah Shin   +2 more
wiley   +1 more source

Sterol absorption and sterol balance in phytosterolemia evaluated by deuterium-labeled sterols: effect of sitostanol treatment.

Journal of Lipid Research, 1995
Absorption of dietary cholesterol, campesterol, and sitosterol, cholesterol balance, and fecal excretion of plant sterols were determined in three unrelated patients with phytosterolemia and three healthy volunteers during constant intake of cholesterol ...
D Lütjohann, I Björkhem, U.F. Beil, K von Bergmann   +3 more
doaj   +1 more source

Influence of Direct Saponification Conditions on Sterol Yield and Composition of the Unsaponifiable Fraction of the Microalga Isochrysis galbana and the Seaweed Ascophyllum nodosum

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Saponification is a key step for recovering the unsaponifiable fraction (USF) of lipids, which contains bioactive sterols, tocopherols, and carotenoids. This study optimized direct saponification conditions (50–300 g L−1 KOH; 60°C–100°C) to recover sterol‐rich USFs from the microalga Isochrysis galbana and the brown seaweed Ascophyllum nodosum,
Mina Zareie, Suzanne M. Budge
wiley   +1 more source