Results 131 to 140 of about 1,486,948 (310)

Pod physical traits significantly implicate shattering response of pods in beans (Phaseolus vulgaris L.)

Biologia Plantarum
Pod shattering is an undesirable process leading to loss of harvestable yields. In the present study, we sought to undertake the first comprehensive phenotyping in 254 bean (Phaseolus vulgaris L.) genotypes for pod shattering including various ...
Samreen FATIMA, Sujeela RANI, Sadiah SHAFI, Aaqif ZAFFAR, Ishrat RIYAZ, M. Altaf WANI, Sajad M. ZARGAR, P.V. VARA PRASAD, Parvaze A. SOFI   +8 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Secondary Organic Aerosol Formation from Healthy and Aphid-Stressed Scots Pine Emissions. [PDF]

, 2019
One barrier to predicting biogenic secondary organic aerosol (SOA) formation in a changing climate can be attributed to the complex nature of plant volatile emissions.
Buchholz, Angela, Faiola, Celia L, Holopainen, Jarmo K, Kari, Eetu, Khalaj, Farzaneh, Kivimäenpää, Minna, Miettinen, Pasi, Pullinen, Iida, Schobesberger, Siegfried, Virtanen, Annele, Yli-Juuti, Taina, Ylisirniö, Arttu   +11 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Using a thermal gradient table to study plant temperature signalling and response across a temperature spectrum

Plant Methods
Plants must cope with ever-changing temperature conditions in their environment. In many plant species, suboptimal high and low temperatures can induce adaptive mechanisms that allow optimal performance.
Myrthe Praat, Zhang Jiang, Joe Earle, Sjef Smeekens, Martijn van Zanten   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Sustainable agriculture through seaweed biostimulants: a two-year study demonstrates yield enhancement in pepper and eggplant

Frontiers in Plant Science
Global climate change and unsustainable agricultural practices have intensified the need for eco-friendly strategies to improve crop resilience and productivity.
Nikola Staykov, Aakansha Kanojia, Rafe Lyall, Valentina Ivanova, Saleh Alseekh, Saleh Alseekh, Veselin Petrov, Veselin Petrov, Tsanko Gechev, Tsanko Gechev   +9 more
doaj   +1 more source

Adapting lowland rice cultivation to climate change - thermal stress tolerance breeding in the Sahel region of West Africa [PDF]

, 2011
The Sahel region of West Africa is characterized by extreme diurnal and seasonal temperature variation subjecting the rice crop to thermal stress at different growth stages.
Dingkuhn, Michaël, Kiepe, Paul, Manneh, Baboucarr, Sow, Abdoulaye   +3 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source