Results 141 to 150 of about 554,740 (316)

The role of SENSITIVE TO FREEZING6 in plant tolerance to stress [PDF]

, 2010
The current rate of climate change predicts that plants will become subject to increasing extremes of enviro nmental stress. Rapid population increases in developing countries also demand higher yield from crop production, often from sub-optimal ...
WATHUGALA-GAMAGE, DEEPTHI,LAKMINI, Wathugala-Gamage, Deepthi Lakmini   +1 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Native Plant Growth-Promoting Rhizobacteria Containing ACC Deaminase Promote Plant Growth and Alleviate Salinity and Heat Stress in Maize (Zea mays L.) Plants in Saudi Arabia

Halotolerant, plant growth-promoting rhizobacteria (PGPR) are known to alleviate plant growth under abiotic stresses, especially those isolated from saline arid soils.
Hend A. Alwathnani, Fahad N. I. AL-Barakah, Fahad Alotaibi, Madeha A. Alonazi   +3 more
core   +1 more source

A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation

, 2018
© 2018 ASPB. Somatic polyploidy caused by endoreplication is observed in arthropods, molluscs, and vertebrates but is especially prominent in higher plants, where it has been postulated to be essential for cell growth and fate maintenance.
Boudolf, Veronique, Cuevas, Fabiola, Beeckman, Tom, Lu, R., Xu, F., Nowack, Moritz, Hofte, H., Smith, Richard S, Lambert, G., Van Isterdael, Gert, De Veylder, L., Smith, Richard, Vercauteren, Ilse, Kumpf, Robert P., Boudolf, V., Kumpf, R., Eekhout, Thomas, Nowack, Moritz K., De Rycke, R., Höfte, Herman, Cuevas, F., Maere, S., Larkin, J., De Rycke, Riet, Kremer, Anna, Xu, Fan, Galbraith, D., Lambert, Georgina M., Lambert, Georgina M, Smith, R., Smith, Richard S., Kremer, A., Nowack, M., Storme, V., Hu, Z., Storme, Veronique, De Veylder, Lieven, Vercauteren, I., Beeckman, T., Bhosale, Rahul, Galbraith, David W., Kumpf, Robert, Maere, Steven, Galbraith, David W, Cuevas Bustamante, Fabiola, Bhosale, R., Larkin, John C, Larkin, John C., Hu, Zhubing, Eekhout, T., Lu, Ran, Van Isterdael, G.   +51 more
core   +1 more source

Pod physical traits significantly implicate shattering response of pods in beans (Phaseolus vulgaris L.)

Biologia Plantarum
Pod shattering is an undesirable process leading to loss of harvestable yields. In the present study, we sought to undertake the first comprehensive phenotyping in 254 bean (Phaseolus vulgaris L.) genotypes for pod shattering including various ...
Samreen FATIMA, Sujeela RANI, Sadiah SHAFI, Aaqif ZAFFAR, Ishrat RIYAZ, M. Altaf WANI, Sajad M. ZARGAR, P.V. VARA PRASAD, Parvaze A. SOFI   +8 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Acetoin Promotes Plant Growth and Alleviates Saline Stress by Activating Metabolic Pathways in Lettuce Seedlings

Acetoin is a volatile organic compound, which is a class of metabolites produced by plant growth-promoting rhizobacteria. The mechanisms underlying plant growth promotion by acetoin and its potential to induce saline stress tolerance in plants are poorly
Jing Leng, Yu Song, Hui Shen, Nan Gao, Shangbo Yan, Chaowei Zhou, Changyi Ma   +6 more
core   +1 more source