Results 81 to 90 of about 62,237 (305)
The surgical management of symptomatic peripheral nerve sheath tumors
, 2010 To determine the clinical presentation and morbidity of the surgical management of peripheral nerve sheath tumors (PNSTs). We performed a retrospective chart review of surgically treated PNSTs at the University of Miami between 1991 and 2008.
Qadir, Rabah +4 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 1987 Bibliography: leaves 102-117An investigation was undertaken into the biology and genetics of Witches' Broom disease on Protea cynaroides. The investigation was approached in two ways: firstly, from a physiological and pathological angle and secondly at ...
Dorrington, Rosemary Ann
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Pediatric germ cell tumors represent a rare but biologically diverse group of neoplasms arising from pluripotent primordial germ cells. The 2022 edition of the WHO Classification of Pediatric Tumors introduced the first organ independent classification ...
Colmenero, Isabel +3 more
core +1 more source
Sugar Partitioning between Ustilago maydis and Its Host Zea mays L during Infection
, 2018 The basidiomycete Ustilago maydis causes smut disease in maize (Zea mays) by infecting all plant aerial tissues. The infection causes leaf chlorosis and stimulates the plant to produce nutrient-rich niches (i.e.
Sosso, Davide +6 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Plant tumors induced by A. tumefaciens: a genetic approach
, 1975 It is shown that a large plasmid in A. tumefaciens cells, called the TI-plasmid, besides being essential for oncogenicity also determines: (1) the specificity and the activity of the enzyme-system for octopine or nopaline utilisation; (2) the synthesis ...
Rörsch, Arthur +4 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source