Results 101 to 110 of about 11,252,242 (248)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Growing Translational Plant Sciences
, 2015 The annual magazine for the Virginia Tech Translational Plant Sciences (TPS) graduate program, formerly Molecular Plant Sciences (MPS)
Translational Plant Sciences +1 more
core
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Phytobiomes JournalTumorigenic agrobacteria are widespread plant pathogens causing crown gall and cane gall diseases in various agricultural crops. These pathogens genetically transform the host plant and thus form an ecological niche (galls) in which specific metabolites (
Nemanja Kuzmanović +11 more
doaj +1 more source
Growing Translational Plant Sciences
, 2016 The annual magazine for the Virginia Tech Translational Plant Sciences (TPS) graduate program, formerly Molecular Plant Sciences (MPS)
Translational Plant Sciences +1 more
core
, 2020 The plant kingdom produces hundreds of thousands of low molecular weight organic compounds. Based on the assumed functions of these compounds, the research community has classified them into three overarching groups: primary metabolites, which are ...
Erb, Matthias, Kliebenstein, Daniel J.
core +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Role of Natural Extracts in the Management of Infantile Hemangiomas and Vascular Tumors
Pediatric Health, Medicine and TherapeuticsIulia Cristina Roca,1,* Elena Cojocaru,2 Carmen Daniela Rusu,1 Laura Mihaela Trandafir,3 Cătălina Iulia Săveanu,4 Vasile Valeriu Lupu,3,* Lăcrămioara Ionela Butnariu,5 Viorel Ţarcă,6,* Mihaela ...
Roca IC +11 more
doaj