Results 121 to 130 of about 11,252,242 (248)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol

Molecules
Cannabidiol (CBD), a non-psychoactive ingredient extracted from the hemp plant, has shown therapeutic effects in a variety of diseases, including anxiety, nervous system disorders, inflammation, and tumors.
Li Ma, Mengke Liu, Chuntong Liu, Huachang Zhang, Shude Yang, Jing An, Guiwu Qu, Shuling Song, Qizhi Cao   +8 more
doaj   +1 more source

A simple method to transfer, integrate and study expression of foreign genes, such as chicken ovalbumin and alpha‐actin in plant tumors.

EMBO Journal, 1984
C. Koncz, F. Kreuzaler, Z. Kálmán, J. Schell   +3 more
semanticscholar   +1 more source

Radiation Therapy for Desmoid Tumors

, 2011
Radiation therapy uses high-energy ionizing radiation beams to treat malignant cancers as well as a variety of benign tumors and medical conditions. James Ewing was the first to report the successful use of radiotherapy in the management of unresectable ...
Chen, Yen-Lin, Hani O. Al-Halabi, Francis J. Hornicek, Mullen, John T., John T. Mullen, Yen-Lin Chen, Sam S. Yoon, Yoon, Sam S., Hornicek, Francis J., DeLaney, Thomas F., Al-Halabi, Hani O., Thomas F. DeLaney   +11 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Proteome and Metabolome Alterations in Radish (Raphanus sativus L.) Seedlings Induced by Inoculation with Agrobacterium tumefaciens

Biomolecules
Infection of higher plants with agrobacteria (Agrobacterium tumefaciens) represents one of the most comprehensively characterized examples of plant–microbial interactions. Incorporation of the bacterial transfer DNA (T-DNA) in the plant genome results in
Nadezhda Frolova, Daria Gorbach, Christian Ihling, Tatiana Bilova, Anastasia Orlova, Elena Lukasheva, Ksenia Fedoseeva, Irina Dodueva, Lyudmila A. Lutova, Andrej Frolov   +9 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Plant-derived extracellular vesicles as a novel tumor-targeting delivery system for cancer treatment

Frontiers in Cell and Developmental Biology
Extracellular vesicles (EVs) are vital mediators of intercellular communication, helping to transfer bioactive molecules to target cells and demonstrating significant potential in antitumor therapy.
Hanjin Wu, Mengya Shi, Liwei Meng, Jie Qiu, Yuancong Jiang, Da Qian, Fengqing Shen   +6 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Phytorhabdoviruses as a regressive factor of plant tumors

, 2012
При инкубировании растительных опухолей, индуцированных Agrobacterium tumefaciens, с различными рабдовирусами — вирусом кучерявой карликовости картофеля (ВККК), вирусом ожога гречихи (ВОГ) и вирусом везикулярного стоматита (ВВС), отмечена регрессия ...
Жидкевич, Н.В., Сабирова, Т.Ю., Юзвенко, Л.В., Диденко, Л.Ф., Лозовая, О.Й., Спивак, Н.Я.   +5 more
core   +1 more source