Results 91 to 100 of about 5,871,411 (406)

Endogenous caulimovirid sequences are widespread in plant genomes [PDF]

open access: yes, 2010
Endogenous sequences from members of the Caulimoviridae and Geminiviridae families have been identified in the genome of several plant species. They are thought to result from illegitimate recombination events and are generally replication-defective ...
Choisne, Nathalie   +6 more
core  

Manipulation of Aphid Behavior by a Persistent Plant Virus

open access: yesJournal of Virology, 2019
This study demonstrates that a persistent plant virus can manipulate aphid behavior. This manipulation is in stark contrast to previously described effects of acute viruses on their hosts that facilitate their transmission.
M. Safari, M. Ferrari, M. Roossinck
semanticscholar   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Characterization and Spike Gene Analysis of a Candidate Attenuated Live Bovine Coronavirus Vaccine

open access: yesAnimals
The bovine coronavirus (BCoV) KBR-1 strain, obtained from calf diarrhea samples collected in 2017, belongs to group GIIa. To attenuate this strain, it was subcultured continuously (up to 79 times) in HRT-18 cells, followed by 80–120 passages in MDBK ...
Gyu-Nam Park   +8 more
doaj   +1 more source

Aphid transmission of Cauliflower mosaic virus: the role of the host plant [PDF]

open access: yes, 2009
Addendum to: Martinière A, Gargani D, Uzest M, Lautredou N, Blanc S, Drucker M. A role for plant microtubules in the formation of transmission-specific inclusion bodies of Cauliflower mosaic virus. Plant J 2009; 58:135-46.
Drucker, Martin   +2 more
core   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Seroprevalence, Genetic Characteristics, and Pathogenicity of Korean Porcine Sapeloviruses

open access: yesViruses
Although porcine sapelovirus (PSV) is generally subclinical, it can cause a wide range of clinical signs in some individuals, including respiratory distress, acute diarrhea, pneumonia, skin lesions, reproductive failure, and neurological diseases.
Song-Yi Kim   +7 more
doaj   +1 more source

Diversity and recombination analysis of Cotton leaf curl Multan virus: a highly emerging begomovirus in northern India

open access: yesBMC Genomics, 2019
Background Cotton leaf curl disease (CLCuD), caused by begomoviruses in association with satellite molecules, is a major threat to cotton production causing enormous losses to cotton crop in most of the cotton growing countries including Indian ...
Razia Qadir   +3 more
doaj   +1 more source

Antiviral activity of chitosan nanoparticles for controlling plant-infecting viruses

open access: yesSouth African Journal of Science, 2022
Chitosan nanoparticles (ChiNPs) are a potentially effective means for controlling numerous plant diseases. This study firstly describes the antiviral capabilities of ChiNPs to control plant viral diseases compared to its bulk form.
Ahmed Y. El Gamal   +4 more
doaj   +1 more source

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