Results 141 to 150 of about 5,758,244 (409)
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Molecular studies on a complex of potyviruses infecting solanaceous crops, and some specific virus-host interactions [PDF]
, 2003 This thesis constitutes a comprehensive analysis of the molecular and biological characteristics of three potyviruses (genus Potyvirus, family Potyviridae) naturally occurring in cultivated and wild species of family Solanaceae: Peru tomato virus (PTV ...
Spetz, Carl
core
Kalanchoë blossfeldiana, a new host for Sonchus yellow net virus [PDF]
The agent causing chlorotic spots in Kalanchoë blossfeldiana `Isabella¿ was investigated. A virus isolated from this naturally infected kalanchoë was mechanically transmissible to several indicator plants.
Balen, E., van +3 more
core +2 more sources
The coevolution of plants and viruses: Resistance and pathogenicity [PDF]
, 2010 Virus infection may damage the plant, and plant defenses are effective against viruses; thus, it is currently assumed that plants and viruses coevolve. However, and despite huge advances in understanding the mechanisms of pathogenicity and virulence in ...
Fraile Pérez, Aurora +1 more
core +3 more sources
Plant Virus–Insect Vector Interactions: Current and Potential Future Research Directions
Viruses, 2016 Acquisition and transmission by an insect vector is central to the infection cycle of the majority of plant pathogenic viruses. Plant viruses can interact with their insect host in a variety of ways including both non-persistent and circulative ...
R. Dietzgen +2 more
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Viruses of cucumber isolated from some regions of Ukraine
Plant Protection Science, 2002 Properties of viruses isolated from cucumbers in greenhouses of Ukraine are characterized in this article by electrophoresis, ELISA, electron microscopy, and immunoblotting.
A. Ryzhkova +3 more
doaj +1 more source
Inter- and Intramolecular recombinations in the Cucumber Mosaic Virus genome related to adaptation to Alstroemeria [PDF]
, 2002 In four distinct alstroemeria-infecting cucumber mosaic virus (CMV) isolates, additional sequences of various lengths were present in the 3' nontranslated regions of their RNAs 2 and 3, apparently the result of intra- and intermolecular recombination ...
Chen, Y.K., Goldbach, R.W., Prins, M.W.
core +4 more sources
Small interfering RNA pathway modulates persistent infection of a plant virus in its insect vector
Scientific Reports, 2016 Plant reoviruses, rhabdoviruses, tospoviruses, and tenuiviruses are transmitted by insect vectors in a persistent-propagative manner. How such persistent infection of plant viruses in insect vectors is established and maintained remains poorly understood.
Hanhong Lan +6 more
semanticscholar +1 more source
PLOS ONE, 2019 Emerging viral diseases, most of which are zoonotic, pose a significant threat to global health. There is a critical need to identify potential new viral pathogens and the challenge is to identify the reservoirs from which these viruses might emerge.
Meesbah Jiwaji +7 more
openaire +4 more sources