Results 81 to 90 of about 5,423,022 (349)

A Framework for the Evaluation of Biosecurity, Commercial, Regulatory, and Scientific Impacts of Plant Viruses and Viroids Identified by NGS Technologies

Frontiers in Microbiology, 2016
Recent advances in high-throughput sequencing technologies and bioinformatics have generated huge new opportunities for discovering and diagnosing plant viruses and viroids.
S. Massart, T. Candresse, J. Gil, C. Lacomme, L. Predajňa, M. Ravnikar, J. Reynard, A. Rumbou, P. Saldarelli, D. Škorić, E. Vainio, J. Valkonen, H. Vanderschuren, C. Varveri, T. Wetzel   +14 more
semanticscholar   +1 more source

Distinct modes of manipulation of rice auxin response factor OsARF17 by different plant RNA viruses for infection

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Auxin signaling plays essential roles in almost every aspect of plant growth and development. Auxin response factors (ARFs) are key transcriptional regulators of auxin signaling.
Hehong Zhang, Lulu Li, Yuqing He, Qingqing Qin, Changhai Chen, Zhongyan Wei, Xiaoxiang Tan, Kaili Xie, Ruifang Zhang, G. Hong, Jing Li, Junmin Li, Chengqi Yan, Fei Yan, Yi Li, Jianping Chen, Zongtao Sun   +16 more
semanticscholar   +1 more source

Viruses in Plants

The American Biology Teacher, 1939
Many people are unaware that plants have diseases,-that they are afflicted by the same pathogenic agents as attack animals and man. Fungi, bacteria, viruses, insects, and nematodes are important agents causing plant maladies. Plants also suffer from serious deficiency diseases.
openaire   +2 more sources

Viruses and Plant Development

, 2018
Peer ...
Sánchez, Flora, Ponz Ascaso, Fernando
openaire   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Geometagenomics illuminates the impact of agriculture on the distribution and prevalence of plant viruses at the ecosystem scale

The ISME Journal, 2017
Disease emergence events regularly result from human activities such as agriculture, which frequently brings large populations of genetically uniform hosts into contact with potential pathogens.
P. Bernardo, T. Charles‐Dominique, M. Barakat, Philippe Ortet, E. Fernandez, D. Filloux, P. Hartnady, Tony A. Rebelo, S. Cousins, F. Mesléard, Damien Cohez, N. Yavercovski, A. Varsani, G. Harkins, M. Peterschmitt, C. Malmstrom, D. Martin, P. Roumagnac   +17 more
semanticscholar   +1 more source

Stability of recombinant plant viruses containing genes of unrelated plant viruses

Journal of General Virology, 2007
The stability of hybrid plant viruses that might arise by recombination in transgenic plants was examined using hybrid viruses derived from the viral expression vectors potato virus X (PVX) and tobacco rattle virus (TRV). The potato virus Y (PVY) NIb and HCPro open reading frames (ORFs) were introduced into PVX to generate PVX-NIb and PVX-HCPro, while ...
Tomas Canto, Peter Palukaitis, Bong-Nam Chung, Bong-Nam Chung   +3 more
openaire   +5 more sources

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Role of the Insect Supervectors Bemisia tabaci and Frankliniella occidentalis in the Emergence and Global Spread of Plant Viruses.

Annual Review of Virology, 2015
Emergence of insect-transmitted plant viruses over the past 10-20 years has been disproportionately driven by two so-called supervectors: the whitefly, Bemisia tabaci, and the Western flower thrips, Frankliniella occidentalis.
R. Gilbertson, O. Batuman, C. Webster, S. Adkins   +3 more
semanticscholar   +1 more source