Results 91 to 100 of about 9,022,422 (292)

Bridging the Structural Gap: A Methodological Review of Cryo-Electron Microscopy for Underrepresented Viruses

open access: yesViruses
Cryo-electron microscopy (cryo-EM) has revolutionized structural virology, enabling routine structure determination at 2–4 Å resolution, with exceptional cases reaching 1.56 Å.
Yoon Ho Park   +3 more
doaj   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Repurposing Plant Virus Nanoparticles

open access: yesVaccines, 2018
Plants have been explored for many years as inexpensive and versatile platforms for the generation of vaccines and other biopharmaceuticals. Plant viruses have also been engineered to either express subunit vaccines or act as epitope presentation systems.
Kathleen L. Hefferon
doaj   +1 more source

Network Analysis of the Papaya Orchard Virome from Two Agroecological Regions of Chiapas, Mexico

open access: yesmSystems, 2020
The study of complex ecological interactions, such as those among host, pathogen, and vector communities, can help to explain host ranges and the emergence of novel pathogens. We evaluated the viromes of papaya orchards, including weed and insect viromes,
Ricardo I. Alcalá-Briseño   +4 more
doaj   +1 more source

Plant Immunity against Viruses

open access: yes, 2017
Plant viruses impose a serious threat on agriculture, which motivates extensive breeding efforts for viral resistant crops and inspires lasting interests on basic research to understand the mechanisms underlying plant immunity against viruses.
Yule Liu, Jian-Zhong Liu, Feng Li
core   +1 more source

Changes in Subcellular Localization of Host Proteins Induced by Plant Viruses

open access: yes, 2021
Viruses are dependent on host factors at all parts of the infection cycle, such as translation, genome replication, encapsidation, and cell-to-cell and systemic movement.
Kaoutar El Mounadi   +2 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Viral coat proteins decrease the gene silencing activity of cognate and heterologous viral suppressors

open access: yesScientific Reports
Plant viruses have evolved different viral suppressors of RNA silencing (VSRs) to counteract RNA silencing which is a small RNA-mediated sequence-specific RNA degradation mechanism.
Dóra Pinczés   +4 more
doaj   +1 more source

Mechanisms of resistance to plant viruses

open access: yes, 1986
27 Pág.This chapter reviews biological phenomena that result in the restriction of plant viruses and the mechanisms of such restriction. By "restriction" we mean reduced replication, accumulation, or spread of the virus in the plant.
Bruening, G., Ponz Ascaso, Fernando
core   +1 more source

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