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Recombinant vaccines for COVID-19 [PDF]

Human Vaccines & Immunotherapeutics, 2020
SARS-CoV-2, the causative agent of COVID-19, has imposed a major public health threat, which needs effective therapeutics and vaccination strategies. Several potential candidate vaccines being rapidly developed are in clinical evaluation. Considering the
Tushar Yadav, Nishant Srivastava, Gourav Mishra, Kuldeep Dhama, Swatantra Kumar, Bipin Puri, Shailendra K Saxena   +6 more
doaj   +2 more sources

Algae-based oral recombinant vaccines

Frontiers in Microbiology, 2014
Recombinant subunit vaccines are some of the safest and most effective vaccines available, but their high cost and the requirement of advanced medical infrastructure for administration make them impractical for many developing world diseases. Plant-based
Mayfield Stephen P
exaly   +3 more sources

Influence of Dosing Regimen and Adjuvant Type on the Immunogenicity of Novel Recombinant Zika Virus-Like Particles

Microbiology Spectrum, 2023
Zika virus (ZIKV) is a reemerging mosquito-borne flavivirus that causes febrile illness and is also linked to Guillain-Barré syndrome as well as to microcephaly in newborns.
Gabriela Brzuska, Boguslaw Szewczyk, Ewelina Krol   +2 more
doaj   +1 more source

The Influence of Adjuvant Type on the Immunogenicity of RBD/N Cocktail Antigens as a Vaccine Candidate against SARS-CoV-2 Virus

Microbiology Spectrum, 2023
The emerging virus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2 virus), agent of COVID-19, appeared in December 2019 in Wuhan, China, and became a serious threat to global health and public safety. Many COVID-19 vaccines have been approved
Gabriela Brzuska, Marta Zimna, Klaudia Baranska, Boguslaw Szewczyk, Petra Strakova, Daniel Ruzek, Ewelina Krol   +6 more
doaj   +1 more source

Genetic Diversity of Type A Influenza Viruses Found in Swine Herds in Northwestern Poland from 2017 to 2019: The One Health Perspective

Viruses, 2023
Influenza A viruses (IAV) are still a cause of concern for public health and veterinary services worldwide. With (−) RNA-segmented genome architecture, influenza viruses are prone to reassortment and can generate a great variety of strains, some capable ...
Lukasz Rabalski, Maciej Kosinski, Piotr Cybulski, Tomasz Stadejek, Krzysztof Lepek   +4 more
doaj   +1 more source

Characterization of Immune Response towards Generation of Universal Anti-HA-Stalk Antibodies after Immunization of Broiler Hens with Triple H5N1/NA-HA-M1 VLPs

Viruses, 2022
(1) Background: Avian influenza viruses (AIVs) promptly evade preexisting immunity by constantly altering the immunodominant neutralizing antibody epitopes (antigenic drift) or by procuring new envelope serotypes (antigenic shift).
Beata Gromadzka, Milena Chraniuk, Lilit Hovhannisyan, Karolina Uranowska, Bogusław Szewczyk, Magdalena Narajczyk, Mirosława Panasiuk   +6 more
doaj   +1 more source

High-Quality Complete Genome Resource of Pathogenic Bacterium Pectobacterium atrosepticum Strain Green1 Isolated from Potato (Solanum tuberosum L.) in Greenland

Molecular Plant-Microbe Interactions, 2021
Pectobacterium atrosepticum is a narrow-host-range, pectinolytic, plant-pathogenic bacterium causing blackleg of potato (Solanum tuberosum L.) worldwide. Till present, several P.
Robert Czajkowski, Lukasz Rabalski, Maciej Kosinski, Eigil de Neergaard, Susanne Harding   +4 more
doaj   +1 more source

Anti-Tick-Borne Encephalitis Virus Activity of Novel Uridine Glycoconjugates Containing Amide or/and 1,2,3-Triazole Moiety in the Linker Structure

Pharmaceuticals, 2020
Tick-borne encephalitis virus (TBEV) transmitted by ticks is a pathogen of great medical importance. As still no effective antiviral treatment is available, in the present study, a series of uridine glycoconjugates containing amide or/and 1,2,3-triazole ...
Gabriela Brzuska, Gabriela Pastuch-Gawolek, Monika Krawczyk, Boguslaw Szewczyk, Ewelina Krol   +4 more
doaj   +1 more source

Recombinant vaccines against Newcastle Disease: current trends and research agenda

Vaccine Research, 2021
Decades after the production of recombinant vaccines, the production of large scale and commercial use of such vaccines has become an important issue in the academic community.
Amir GHaffar Shahriari, Maziar Habibi
doaj   +1 more source

Review of candidate vaccines for the prevention of Lassa fever

Вопросы вирусологии, 2021
The Lassa virus one of the main etiological agent of hemorrhagic fevers in the world: according to WHO estimates, it affects 100,000 to 300,000 people annually, which results in up to 10,000 deaths [1].
O. D. Popova, O. V. Zubkova, T. A. Ozharovskaia, D. I. Zrelkin, D. V. Voronina, I. V. Dolzhikova, D. V. Shcheblyakov, B. S. Naroditsky, D. Yu. Logunov, A. L. Gintsburg   +9 more
doaj   +1 more source