Results 81 to 90 of about 9,022,422 (292)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Framework for the Evaluation of Biosecurity, Commercial, Regulatory, and Scientific Impacts of Plant Viruses and Viroids Identified by NGS Technologies

Frontiers in Microbiology, 2017
Recent advances in high-throughput sequencing technologies and bioinformatics have generated huge new opportunities for discovering and diagnosing plant viruses and viroids.
S. Massart, T. Candresse, J. Gil, C. Lacomme, L. Predajňa, M. Ravnikar, J. Reynard, A. Rumbou, P. Saldarelli, D. Škorić, E. Vainio, J. Valkonen, H. Vanderschuren, C. Varveri, T. Wetzel   +14 more
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Development of the Large-Scale Oligonucleotide Chip for the Diagnosis of Plant Viruses and its Practical Use

The Plant Pathology Journal, 2014
A large-scale oligonucleotide (LSON) chip was developed for the detection of the plant viruses with known genetic information. The LSON chip contains two sets of 3,978 probes for 538 species of targets including plant viruses, satellite RNAs and viroids.
Moon Nam, Jeong-Seon Kim, Seungmo Lim, Chung Youl Park, Jeong-Gyu Kim, Hong-Soo Choi, Hyoun-Sub Lim, Jae Sun Moon, Su-Heon Lee   +8 more
doaj   +1 more source

Post-COVID-19 Action: Guarding Africa’s Crops against Viral Epidemics Requires Research Capacity Building That Unifies a Trio of Transdisciplinary Interventions

Viruses, 2020
The COVID-19 pandemic has shown that understanding the genomics of a virus, diagnostics and breaking virus transmission is essential in managing viral pandemics. The same lessons can apply for plant viruses.
Francis O. Wamonje
doaj   +1 more source

Plant viruses and bacteriophages for drug delivery in medicine and biotechnology

Current Opinion in Chemical Biology, 2017
There are a wide variety of synthetic and naturally occurring nanomaterials under development for nanoscale cargo-delivery applications. Viruses play a special role in these developments, because they can be regarded as naturally occurring nanomaterials ...
Anna E. Czapar, N. Steinmetz
semanticscholar   +1 more source

Top 10 plant viruses in molecular plant pathology [PDF]

, 2011
Many scientists, if not all, feel that their particular plant virus should appear in any list of the most important plant viruses. However, to our knowledge, no such list exists.
Scholthof, K-BG, Hemenway, C, Candresse, Thierry,, HENRYK CZOSNEK, Ahlquist, Paul, Saunders, Keith, Hohn, Thomas, Ahlquist, P, KEITH SAUNDERS, BARBARA HOHN, Candresse, T, Jacquot, Emmanuel, PAUL AHLQUIST, CYNTHIA HEMENWAY, Adkins, S, KAREN-BETH G. SCHOLTHOF, PETER PALUKAITIS, Hohn, T, Czosnek, Henryk, SCOTT ADKINS, EMMANUEL JACQUOT, Hohn, B, Candresse, Thierry, Hemenway, Cynthia, Palukaitis, P, Czosnek, H, Foster, Gary D., Scholthof, Karen-Beth G., Foster, GD, Jacquot, E, Saunders, K, THOMAS HOHN, THIERRY CANDRESSE, GARY D. FOSTER, Hohn, Barbara, Adkins, Scott, Palukaitis, Peter, Valencia Jiménez, Arnubio, Sánchez, Manuel Alejandro, Villegas Estrada, Bernardo   +39 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Application of Plant Viruses as a Biotemplate for Nanomaterial Fabrication

Molecules, 2018
Viruses are widely used to fabricate nanomaterials in the field of nanotechnology. Plant viruses are of great interest to the nanotechnology field because of their symmetry, polyvalency, homogeneous size distribution, and ability to self-assemble.
Yu Zhang, Yixin Dong, Jin-Hua Zhou, Xun Li, Fei Wang   +4 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source