Results 121 to 130 of about 11,010,391 (302)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Assessing integrated water status in drip-irrigated maize fields using UAV multispectral data and machine learning algorithms

Agricultural Water Management
Accurate monitoring of farmland water status is critical for improving water resource use efficiency and enhancing agricultural system resilience. Monitoring either soil moisture content or plant water content alone fails to reveal the overall water ...
Mingjie Ma, Jinghua Zhao, Ming Hong, Tingrui Yang, Qiuping Fu   +4 more
doaj   +1 more source

Validation of thermal indices for water status identification in grapevine

, 2014
The use of thermal imaging represents a substantial progress in monitoring plant water status and therefore drought stress in field conditions. However, the effective use of thermal imaging requires consistent methods for data acquisition and image ...
Medrano, H. [0000-0002-6742-5746], Pou, A. [0000-0001-9664-5038], Baluja, J., Tardaguila, J. [0000-0002-6639-8723], Diago, M.P. [0000-0003-4049-0879]   +4 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Effect of Deficit Irrigation on Agronomic and Physiological Performance of Young Persimmon (Diospyros kaki Thunb.) Trees

Agronomy
This article addresses the impact of deficit irrigation on the agronomic and physiological performance of “Rojo Brillante” persimmon trees in a Mediterranean climate.
Rossana Porras-Jorge, José Mariano Aguilar, Carlos Baixauli, Bernardo Pascual, Nuria Pascual-Seva   +4 more
doaj   +1 more source

Water in the 2007 Virginia General Assembly

, 2007
The 2007 Virginia General Assembly convened January 10, adjourned February 24, and held a reconvened (“veto”) session on April 4. During the session, the Assembly considered 3427 measures (3069 introduced in this session and 358 continued from the 2006 ...
Virginia Water Resources Research Center
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Development of a risk based model for use in water quality monitoring [PDF]

, 2012
Modelling has recently emerged as an effective and efficient tool in the area of water quality monitoring with new models taking in vast quantities of data and facilitating the development of more targeted water monitoring programs.
Jones, Lisa
core   +2 more sources

Implications of root morphology and anatomy for water deficit tolerance and recovery of grapevine rootstocks

Frontiers in Plant Science
The intensification of drought conditions due to climate change poses a major challenge to sustainable grape production. Rootstocks are essential in supporting grapevine water uptake and drought resilience; however, their physiological responses to water
David Alonso-Forn, David Alonso-Forn, Ignacio Buesa, Ignacio Buesa, Luis Flor, Antoni Sabater, Hipólito Medrano, Hipólito Medrano, José M. Escalona, José M. Escalona   +9 more
doaj   +1 more source