Results 101 to 110 of about 321,398 (342)

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Muscle fatigue degrades force sense at the ankle joint

, 2008
To investigate the effects of muscle fatigue on force sense at the ankle joint, 10 young healthy adults were asked to perform an isometric contra-lateral force ankle-matching task in two experimental conditions of: (1) no-fatigue and (2) fatigue of the ...
Borg, Brockett, Carson, Gandevia, Jones, Ledin, Matthieu Boisgontier, Nicolas Vuillerme, Noda, Proske, Schmidt, Vuillerme, Vuillerme, Vuillerme, Weerakkody   +14 more
core   +3 more sources

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

A COMPARITIVE STUDY ON EFFECTIVENESS OF TAPING WITH IONTOPHORESIS AND TAPING ALONE IN CHRONIC PLANTAR FASCITIS

International Journal of Physiotherapy, 2016
Background: Plantar fasciitis is a painful condition caused by microtrauma to plantar fascia due to overuse. It is a most common cause of heel pain in runners. Various studies proved taping and Iontophoresis as effective in the treating plantar fasciitis.
Dr. Biju Chetri , Dr. U.T. Ifthikar Ali , Dr. Madhusmita Koch, Dr. Abhijit Dutta   +3 more
doaj   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Let me Google that for you:a time series analysis of seasonality in internet search trends for terms related to foot and ankle pain [PDF]

, 2015
BACKGROUND: The analysis of internet search traffic may present the opportunity to gain insights into general trends and patterns in information seeking behaviour related to medical conditions at a population level.
A Moshirfar, BR Waterman, DJ Hawley, DL Scher, H Wickham, HA Carneiro, J Powell, James Woodburn, L Paul, MJ Thomas, P Tucker, R Bratucu, Scott Telfer, SV Nuti   +13 more
core   +1 more source

Curved Retrograde TTC Fusion Nails

Foot & Ankle Orthopaedics, 2017
Category: Hindfoot Introduction/Purpose: Retrograde intramedullary nailing is an established surgical procedure for tibiotalocalcaneal (TTC) fusion. The clinical incidence of plantar neurovascular damage secondary to TTC is poorly reported. Neurovascular
Cesar de Cesar Netto MD, PhD, Ashish Shah MD, David Johannesmeyer MD, Ibukunoluwa Araoye MS, Parke Hudson BS, Bahman Sahranavard MD, Sung Lee BS, Michael Johnson MD, Zachariah Pinter BS, Brent Cone BS   +9 more
doaj   +1 more source

Correlation Between Prolonged Standing And Plantar Fasciitis [PDF]

, 2017
Background: Plantar fasciitis (PF) is the most common heel pain in adult. It is estimated that it affects as much as 10% of the population over the course of their lifetime. Previous study mention that prolonged standing is one of the risk factor of PF,
Bayusentono, S. (Sulis), Dewanti, L. (Linda), Purvitagiri, N. K. (Ni), Wardhani, I. L. (Indrayuni)   +3 more
core  

Initial foot contact patterns during steady state shod running [PDF]

, 2013
C
Breine, Bastiaan, De Clercq, Dirk, Frederick, Edward C, Malcolm, Philippe   +3 more
core   +2 more sources

AI‐Assisted Self‐Powered Wearable Dual‐Mode Sensor With TENG and Stretchable Optical Fiber for Neurological Disorder Diagnostics

Advanced Science, EarlyView.
This manuscript presents the WDMS platform, an AI‐assisted, self‐powered wearable dual‐mode sensor for tele‐neurology. It integrates a contact–separation TENG insole with stretchable polyurethane optical‐fiber strain sensors to synchronously track plantar pressure and lower‐limb muscle deformation.
Tianliang Li, Han Liu, Guoxu Liu, Qian'ao Wang, Haotian Zhou, Guiyi Liu, Yan Xu, Jun Wang, Zuqiang Wang, Feng Zhu, Feiling Luo, Zhong Lin Wang, Chi Zhang   +12 more
wiley   +1 more source