Results 121 to 130 of about 87,003 (262)

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

open access: yesAllergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery   +25 more
wiley   +1 more source

Expanding the Phenotype of PARK‐PRKN to Spastic Paraplegia: A Report of Two Cases

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Nicolas Geoffre   +5 more
wiley   +1 more source

Partial amputation regrowth of P4 distal digit in an eastern grey kangaroo (Macropus giganteus): a case report

open access: yesAustralian Veterinary Journal, EarlyView.
This case report describes distal regrowth of the fourth hind digit (P4) following traumatic autoamputation in a young adult eastern grey kangaroo (Macropus giganteus). Injury to P4 is generally considered to carry a poor prognosis due to its critical role in weight‐bearing and propulsion during hopping.
L Cummins, G Cummins, J Clough, A Shen
wiley   +1 more source

Returning to Marathons: Complete Restoration of Exercise with Runner's Dystonia After Globus Pallidus Internus Deep Brain Stimulation

open access: yes
Movement Disorders, EarlyView.
Arthur Thevathasan   +3 more
wiley   +1 more source

Morphometric and Paleobiological Insights Into Pleistocene Sicilian Wolf Populations

open access: yesActa Zoologica, EarlyView.
ABSTRACT The Pleistocene wolves (Canis lupus) from Sicily represent one of the few known insular populations of this species from that time period. Despite their potential relevance for understanding carnivore adaptations in insular contexts, no dedicated study has previously investigated their morphology and evolutionary significance.
Domenico Tancredi   +3 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade   +7 more
wiley   +1 more source

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