Results 121 to 130 of about 58,273 (309)

Effects and Value of Verifiable Information in a Controversial Market: Evidence from Lab Auctions of Genetically Modified Food [PDF]

Food products containing genetically modified (GM) ingredients have entered the market over the past decade. The biotech industry and environmental groups have disseminating conflicting private information about GM foods.
Huffman, Wallace, Tegene, Abebayehu, Rousu, Matthew, Shogren, Jason F.   +3 more
core  

General Surveillance for Effects of GM Crops on the Soil Ecosystem (Poster Presentation at the 4th International Workshop on PMEM of Genetically Modified Plants, Quedlinburg, Germany 2010)

, 2011
Die EU-Richtlinie 2001/18/EG schreibt vor, dass der Anbau von transgenen Pflanzen durch eine Allgemeine Beobachtung der Auswirkungen begleitet wird, um etwaige, unvor­hergesehene schädliche Effekte aufzudecken.
Glandorf, Boet, Bergmans, Hans, Smit, Eric, Glandorf, Boer   +3 more
core   +1 more source

Impact of genetically modified organisms on meat quality

Open Veterinary Journal
A unique class of gene biotechnology known as genetic modification modifies the genetic makeup of living things like microbes, plants, and animals. Several possible advantages and hazards associated with gene biotechnology. Due to increased food demands
Muntaha Ghazi Hasan
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Hybridization between transgenic and wild plants: environmental risk

Revista Colombiana de Biotecnología, 2011
Genetically modified products are widely commercialized in agricultural production. These include resistant plants to diseases, insects or herbicides, plants with capacity for longer storing times or better nutritional quality.
Alejandro Chaparro Giraldo
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Post-Moratorium EU Regulation of Genetically Modified Products: Trade Concerns

Trade in genetically modified (GM) products remains a major issue in agricultural trade policy. In particular, the European Union has sought to deny market access to GM-products.
Yeung, May T., Kerr, William A., Viju, Crina   +2 more
core  

Tropical Fruit Virus Resistance in the Era of Next-Generation Plant Breeding

SynBio
Plant viral diseases constitute a major contributor to agricultural production losses, significantly impacting the economies of exporting countries by more than USD 30 billion annually. Understanding and researching the biology and genomics of viruses is
Marcella Silva Vieira, Rafael Lara Rezende Cabral, Luíza Favaratto, Laiane Silva Maciel, André da Silva Xavier, Francisco Murilo Zerbini, Patricia M. B. Fernandes   +6 more
doaj   +1 more source