The Enhancement of Abiotic Stress Tolerance in <i>Arabidopsis</i> via Heterologous Overexpression of <i>TcDHN1</i>, a Dehydrin Identified in the Recalcitrant Seeds of <i>Taxillus chinensis</i>. [PDF]
Qin Y +10 more
europepmc +1 more source
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Understanding the metabolome of four stress-relieving and cognitive-enhancing medicinal plants: a comprehensive HR-LC-ESI-MS/MS analysis. [PDF]
Khan MN +3 more
europepmc +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Current Knowledge and Utilization of Medicinal Plants and Fungi in Northeastern Croatia. [PDF]
Krstin L +4 more
europepmc +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Indigenous knowledge on the uses and conservation of medicinal plants in Namutumba District, Eastern Uganda. [PDF]
Tugume P +4 more
europepmc +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
The Influence of the Environment and the Use of Woody Plants: New Evidence for the Ecological Apparency Hypothesis. [PDF]
de Almeida KC +2 more
europepmc +1 more source

