Results 81 to 90 of about 441,720 (277)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Review on Pharmacological, Cultivation and Biotechnology Aspects of Milk Thistle (Silybum marianum (L.) Gaertn.)

Journal of Medicinal Plants, 2013
Milk thistle (Silybum marianum (L.) Gaertn.) is one of the valuable medicinal plants which used in the treatment of liver disorders. The major active constituents in this plant are flavonolignans, collectively known as silymarin which is a mixture of ...
N Qavami, H Naghdi Badi, MR Labbafi, A Mehrafarin   +3 more
doaj  

Process optimization for green synthesis of iron nanoparticles by extract of fenugreek (Trigonella foenum-graecum L.) seeds

Journal of Medicinal Plants, 2022
Background: The green synthesis of nanoparticles using plants presents important advantages over other biological systems. Natural compounds present in plant extracts can reduce metal ions to nanoparticles in a single-step green synthesis process.
Reza Ghafarzadegan, Mahdi Yaghoobi, Saeideh Momtaz, Nasim Ashoory, Mona Ghiaci Yekta, Reza Hajiaghaee   +5 more
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Rapid Micropropagation of Lemon Verbena (Lippia citriodora L.) Using In vitro Culture

Journal of Medicinal Plants, 2012
Background: The genus Lippia contains more than 200 species that Lemon verbena (Lippia citriodora) has a high medicinal value. Therefore expansion of its acreage using development of rapid and new propagation methods has a high importance. Objective: The
A Oladzad, A Qaderi, H Naghdi Badi, AR Zare   +3 more
doaj  

Migration and Ethnobotanical Practices: The Case of Tifey Among Haitian Immigrants in Cuba [PDF]

Ethnobotanical knowledge and practices are dynamic and they change as they are transferred and appropriated by people who are adapting to new surroundings and changing environments.
Beyra, A., Godinez, D., Volpato, G.
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Screening of Indonesia Medicinal Plants Producing Quorum Sensing Inhibitor [PDF]

, 2011
Antibiotic resistance of bacteria lead to create different way in the pathogen bacteria handling such us inhibit their quorum sensing mechanism. The goal of this study is to search quorum sensing inhibitor of seven Indonesia medicinal plants.
Artadana, Ida Bagus Made, Kok, Tjie, Liana, Anny, Prilianti, Kestrilia Rega, Putra, Sulistyo Emantoko Dwi, Rusady, Hendry, Savitri, Savitri, Suryadjaja, Ernest   +7 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Analytical Review on Persian Poppy (Papaver bracteatum Lindl.) as a Native and Economical Medicinal Plant

Journal of Medicinal Plants, 2013
Persian poppy or great scarlet poppy (Papaver bracteatum Lindl.) is proposed as a new source of raw material for codeine production and addiction treatment. This species as a native plant is growing in North and West of Iran.
A Foroozandeh-Shahraki, A Mehrafarin, S Akhondzadeh, H Naghdi Badi, A Qaderi, R Hajiaghaee, F Khalighi-Sigaroodi, M Ghorbani Nahooji   +7 more
doaj