Results 101 to 110 of about 205,606 (312)

Relative antioxidant activity of Brazilian medicinal plants for gastrointestinal diseases

, 2011
The free radical scavenging capacity of Brazilian medicinal plants and some of their constituents was examined in vitro using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) quantitative assay.
Kitagawa, Rodrigo R., Sannomiya, Miriam, Vilegas, Wagner, Bonacorsi, Cibele, da Fonseca, Luiz Marcos, Raddi, Maria Stella G.   +5 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Characterization of coumarins from Ipomoea mauritiana Jacq by LC-APCI-MS/MS analysis and evaluation of its anti-amnesic activity

Beni-Suef University Journal of Basic and Applied Sciences, 2019
Background Ipomoea mauritiana is one of the source plants of Vidari, an Ayurvedic drug used as Medhyarasayana (rejuvenating drug). In this current study, coumarins were separated from tuberous root of I.
Sulaiman C.T, Deepak M, Sunil A.R, Lijini K.R, Indira Balachandran   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Changes in Essential Oil Composition and Leaf traits of Basil (Ocimum basilicum L.) Affected by Bio-stimulators / fertilizers Application

Journal of Medicinal Plants, 2013
Background: Basil (Ocimum basilicum L.), a member of the Lamiaceae family, has traditionally been used as a medicinal plant in the treatment of headaches, coughs, diarrhea, constipation, warts, worms, and kidney malfunctions.
A Rahimi Shokooh, MR Dehghani-Meshkani, A Mehrafarin, F Khalighi-sigaroodi, H Naghdi Badi   +4 more
doaj  

Indigenous knowledge and use of medicinal plants among the Kuria communities in the Tarime and Serengeti districts of Mara Region, Tanzania

, 2023
This study documented indigenous knowledge and use of medicinal plants among the Kuria communities in Mara Region, Tanzania. Ethnobotanical data were collected in collaboration with 20 traditional healers (THs), by jungle-walk-and-identify, field guides ...
Koni Muluwa, Joseph, Bostoen, KoenLW210019932941238010019599620000-0003-2284-6165FB3B7690-F0ED-11E1-A9DE-61C894A0A6B4, Charwi, Mary Zacharia, Mogha, Neema Gideon   +3 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Review on Anatomical, Phytochemical and Pharmacological Properties of Peppermint (Mentha piperita L.)

Journal of Medicinal Plants, 2019
Peppermint (Mentha piperita L.) is native to Mediterranean region which cultivated for food, pharmaceutical, and perfumery uses in all over the world.
M Seif sahandi, A Mehrafarin, F Khalighi-Sigaroodi, M Sharifi, H Naghdi badi   +4 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Changes in Essential Oil Content and Composition of Peppermint (Mentha piperita L.) in Responses to Nitrogen Application

Journal of Medicinal Plants, 2019
Background: Nitrogen is the most important nutrient requirement for plants. Nitrogen supplying affected the leaf area, carbon fixation, glandular trichomes formation, ATP and NADPH content which resulted to the terpenoids biosynthesis enhancement and ...
M Seif Sahandi, H Naghdi Badi, A Mehrafarin, F Khalighi-Sigaroodi, M Sharifi   +4 more
doaj