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The dental plaque biofilm matrix

open access: yesPeriodontology 2000, 2021
The extracellular matrix is a critical component of microbial biofilms, such as dental plaque, maintaining the spatial arrangement of cells and coordinating cellular functions throughout the structure. The extracellular polymeric substances that comprise
Steven D Goodman   +2 more
exaly   +2 more sources

Plaque formation and isolation of pure lines with poliomyelitis virus [PDF]

open access: yesJournal of Experimental Medicine, 1954
Plaques have been produced with the three types of poliomyelitis viruses on monolayer tissue cultures of monkey kidney and monkey testis. The number of plaques was proportional to the concentration of the virus.
Dulbecco, R., Vogt, Marguerite
core   +4 more sources

Coronary artery plaque characteristics and treatment with biologic therapy in severe psoriasis: results from a prospective observational study

open access: yesCardiovascular Research, 2019
AIMS The use of biologic therapy has increased over the past decade well beyond primary autoimmune diseases. Indeed, a recent trial using an anti-IL-1beta antibody reduced second myocardial infarction (MI) in those who have had MI. Psoriasis is a chronic
Amit K Dey   +2 more
exaly   +2 more sources

Inflammation during the life cycle of the atherosclerotic plaque.

open access: yesCardiovascular Research, 2021
Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed, inflammatory mediators likely link many traditional and emerging risk factors with atherogenesis.
P. Libby
semanticscholar   +1 more source

Biologics May Prevent Cardiovascular Events in Rheumatoid Arthritis by Inhibiting Coronary Plaque Formation and Stabilizing High-Risk Lesions. [PDF]

open access: yes, 2020
ObjectiveTo evaluate whether biologic disease-modifying antirheumatic drugs (DMARDs) decrease cardiovascular disease (CVD) risk in rheumatoid arthritis (RA) and whether biologic DMARDs might have a beneficial effect on coronary plaque formation or ...
Budoff, Matthew J   +3 more
core   +1 more source

Quantification of atherosclerotic plaque volume in coronary arteries by computed tomographic angiography in subjects with and without diabetes. [PDF]

open access: yes, 2020
BackgroundDiabetes mellitus (DM) is considered a cardiovascular risk factor. The aim of this study was to analyze the prevalence and volume of coronary artery plaque in patients with diabetes mellitus (DM) vs. those without DM.MethodsThis study recruited
An, Yun-Qiang   +6 more
core   +1 more source

Characterization of bacteriophage communities and CRISPR profiles from dental plaque. [PDF]

open access: yes, 2014
BackgroundDental plaque is home to a diverse and complex community of bacteria, but has generally been believed to be inhabited by relatively few viruses.
Abeles, Shira R   +4 more
core   +2 more sources

Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]

open access: yes, 2016
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B.   +7 more
core   +1 more source

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

open access: yesJournal of Neuroscience, 2006
Mutations in the genes for amyloid precursor protein (APP) and presenilins (PS1, PS2) increase production of β-amyloid 42 (Aβ42) and cause familial Alzheimer's disease (FAD).
Holly Oakley   +11 more
semanticscholar   +1 more source

Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stage [PDF]

open access: yes, 2019
Dental calculus, calcified oral plaque biofilm, contains microbial and host biomolecules that can be used to study historic microbiome communities and host responses.
CJ Adler   +69 more
core   +4 more sources

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