Results 201 to 210 of about 503,732 (331)

Glucocorticoid‐Induced TNFR‐Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children

Pediatric Discovery, EarlyView.
Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li, Yan Li, Jinying Xiang, Yinying Ren, Mi Zhou, Fang Deng, Zhou Fu, Fengxia Ding   +7 more
wiley   +1 more source

Decreased multidrug resistance protein 1 and increased platelet activation in obstructive sleep apnea syndrome

Sleep Research, EarlyView.
There was a positive correlation between apnea/hypopnea index (AHI) index and platelet aggregation and a negative correlation between CD42b and multidrug resistance protein 1 (MRP1). Platelet activation was high while MRP1 expression was low in severe obstructive sleep apnea syndrome (OSAS) independent of smoking, age, and gender.
Cigdem Bayram Gurel, Engin Korkmaz, Suzan Adin Cinar, Gülsel Ayaz, Bulent Tutluoglu, Gunnur Deniz, Arzuhan Koç, Turgut Ulutin, Gonul Kanigur   +8 more
wiley   +1 more source

Targeted and Biomimetic Nanoparticles for Atherosclerosis Therapy: A Review of Emerging Strategies. [PDF]

Biomedicines
Bartusik-Aebisher D, Podgórski R, Serafin I, Aebisher D.   +3 more
europepmc   +1 more source

AMP-Activated Protein Kinase Alpha 2 Deletion Induces VSMC Phenotypic Switching and Reduces Features of Atherosclerotic Plaque Stability.

Circulation Research, 2016
Ye Ding, Miao Zhang, Wencheng Zhang, Qiulun Lu, Zhejun Cai, P. Song, I. Okon, Lei Xiao, M. Zou   +8 more
semanticscholar   +1 more source

Retraction: Overexpressed miR‐335‐5p Reduces Atherosclerotic Vulnerable Plaque Formation in Acute Coronary Syndrome

Journal of Clinical Laboratory Analysis, EarlyView.
RETRACTION: Sun D. Ma T. Zhang Y. Zhang F. Cui B. Overexpressed miR‐335‐5p Reduces Atherosclerotic Vulnerable Plaque Formation in Acute Coronary Syndrome Journal of Clinical Laboratory Analysis 35, no. 2 (2021): e23608 https://doi.org/10.1002/jcla.23608 The above article, published online on 5 December 2020 in Wiley Online Library (http://onlinelibrary.
wiley   +1 more source

Positron Emission Tomography/Computed Tomography Imaging‐Guided Polydopamine Nanoparticles Attenuate Foam Cell Ferroptosis for Targeted Antiatherosclerotic Therapy

Small Science, EarlyView.
Folate‐ and arginine‐modified polydopamine nanoparticles (FPLG NPs) are designed for the specific targeting of atherosclerotic foam cells. These nanoparticles combat ferroptosis by scavenging reactive oxygen species, regulating iron/lipid metabolism, and upregulating the GPX4/NRF2 pathway. Using chelator‐free 68Ga‐labeling, positron emission tomography/
Ximei Dai, Zhiyue Wang, Jiaqi Lu, Yutong Xu, Xingji Liu, Jianchen Qi, Tao Zheng, Feng Wang, Guangming Lu, Longjiang Zhang, Jie Sheng, Guifen Yang   +11 more
wiley   +1 more source

MRI ensemble model of plaque and perivascular adipose tissue as PET-equivalent for identifying carotid atherosclerotic inflammation. [PDF]

EJNMMI Res
Yu F, Li X, Zhang Y, Shan Y, Cui B, Jiao L, Lu J.   +6 more
europepmc   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source

SPTBN1 overexpression ameliorates atherosclerosis by inhibiting oxidative stress and inflammation via regulating the TRIM37/TRAF2/NF-κB pathway. [PDF]

Eur J Med Res
Wu S, Tan X, Cheng G.
europepmc   +1 more source

Atherosclerosis after pre‐eclampsia: systematic review and meta‐analysis

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective Pre‐eclampsia complicates up to 8% of pregnancies and is associated with increased risk of ischemic cardiac and cerebral disease, which may be prevented through management of cardiovascular risk when early disease stages are detected.
G. Jansen, A. De Rooy, E. Janssen, S. Altintas, A. van 't Hof, C. Mihl, B. Kietselaer, M. Spaanderman, C. Ghossein‐Doha   +8 more
wiley   +1 more source