Results 221 to 230 of about 82,317 (266)
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Devouring atherosclerotic plaques
Nature Nanotechnology, 2020Targeting of local macrophages by functionalized carbon nanotubes enables efferocytosis and clearance of atherosclerotic plaques.
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Atherosclerotic plaque development
The International Journal of Biochemistry & Cell Biology, 2009Atherosclerosis is now recognized as an inflammatory/immunomodulatory reaction to the presence of oxidized low-density lipoproteins within the arterial wall, often times in the setting of such risk factors as family history, hypercholesterolemia, high blood pressure, diabetes mellitus and smoking.
Quang T, Bui +2 more
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Development of atherosclerotic plaques
Acta Medica Scandinavica, 1985ABSTRACT. Atherosclerosis is a multifactorial disease. A unified model for the lesion development reveals many connections between the response‐to‐injury hypothesis and the lipid hypothesis. Various cellular uptake mechanisms for native and modified lipoproteins are discussed with respect to foam cell formation and lesion development.
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Investigation of Atherosclerotic Plaque Vulnerability
2022Histochemical and immunohistochemical approaches permit the detection and evaluation of proteins and cell types within murine brachiocephalic artery atherosclerotic plaques, that can be subsequently analyzed to provide inferences on atherosclerotic plaque vulnerability.
George, Sarah J, Johnson, Jason L
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MR imaging of atherosclerotic plaque
Radiologic Clinics of North America, 2002MRI is a powerful noninvasive imaging tool with high spatial resolution that continues to prove its value in determining atherosclerotic plaque size, volume, and tissue components. Multispectral MRI sequences have been validated to characterize atherosclerotic plaque components in animals; they have recently been applied to human aorta and carotid ...
C Joon, Choi, Christopher M, Kramer
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2009
Even though coronary, cerebral, and peripheral arterial disease represents the most common features of atherosclerosis, it progresses in the absence of any symptoms for most of its developmental course. Generally, the severity of a coronary stenosis is of poor predictive value for cardiac events such as sudden death, myocardial infarction, or unstable ...
Maddalena Piro +2 more
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Even though coronary, cerebral, and peripheral arterial disease represents the most common features of atherosclerosis, it progresses in the absence of any symptoms for most of its developmental course. Generally, the severity of a coronary stenosis is of poor predictive value for cardiac events such as sudden death, myocardial infarction, or unstable ...
Maddalena Piro +2 more
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Is regression of atherosclerotic plaque possible?
Clínica e Investigación en Arteriosclerosis (English Edition), 2017As it is well-known, a thrombus evolving into a disrupted/eroded atherosclerotic plaque causes most acute coronary syndromes. Plaque stabilization via reduction of the lipid core and/or thickening of the fibrous cap is one of the possible mechanisms accounted for the clinical benefits displayed by different anti-atherosclerotic strategies.
José A, Páramo, Fernando, Civeira
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Impact of Statins on Atherosclerotic Plaque
Future Cardiology, 2007Lowering levels of low-density lipoprotein cholesterol with inhibitors of 3-hydroxy-methylglutaryl coenzyme A reductase (statins) has a profound impact on cardiovascular event rates. The degree of benefit is proportional to the extent of low-density lipoprotein cholesterol lowering achieved. In addition to lowering levels of atherogenic lipids, statins
Stephen J, Nicholls +2 more
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Evaluation of Coronary Atherosclerotic Plaques
Cardiology Clinics, 2009In many patients, unheralded myocardial infarction associated with a mortality of approximately 20% is the first manifestation of coronary artery disease. Approximately 40% of the population is considered to have a moderate midterm risk of 10% to 20%. Any of the stratification schemes suffers from a lack of accuracy to correctly determine the risk, and
Christoph R, Becker, Tobias, Saam
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Cell death in atherosclerotic plaques
Current Opinion in Lipidology, 1996The investigation of the mechanisms of cell death in atherosclerosis has recently received added impetus with the realization that apoptosis is probably the predominant mechanism. This review examines the preliminary data on mechanisms of cell death in the atherosclerotic plaque.
M J, Mitchinson +2 more
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