Results 91 to 100 of about 1,082,648 (349)
ApoE facilitates the microglial response to amyloid plaque pathology
Journal of Experimental Medicine, 2018 One of the hallmarks of Alzheimer’s disease is the presence of extracellular diffuse and fibrillar plaques predominantly consisting of the amyloid-&bgr; (A&bgr;) peptide.
J. Ulrich +14 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Biomimetic, suturable, biodegradable fibrous scaffolds are engineered to mimic the tensile properties of LUT tissue using photocrosslinked 5:5% weight per volume elastin‐like peptide and methacrylated gelatin (5E5G). In vitro, urothelium, smooth muscle, and fibroblast 7 day cytocompatibility is demonstrated.
Renea M. Sturm +18 more
wiley +1 more source
Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model
Advanced Healthcare Materials, EarlyView.A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark +9 more
wiley +1 more source
The relevance of Randall′s plaques
Indian Journal of Urology, 2014 The pathophysiology of nephrolithiasis is not fully understood. The pioneering work of Alexander Randall in the 1940s sought to clarify our understanding of stone formation. This review traces the inception of the theory of Randall's plaques and the refinement of the hypothesis in the early days of kidney stone research.
Ruth Strakosha +2 more
openaire +4 more sources
Advanced Healthcare Materials, EarlyView.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior
Advanced Healthcare Materials, EarlyView.Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier +3 more
wiley +1 more source
On the Plaque Expansivity Conjecture [PDF]
, 2015 It is one of the main properties of uniformly hyperbolic dynamics that points of two distinct trajectories cannot be uniformly close one to another. This characteristics of hyperbolic dynamics is called expansivity.
Kryzhevich, Sergey
core
Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells
Nature Communications, 2018 Smooth muscle cells (SMCs) play a key role in atherogenesis. However, mechanisms regulating expansion and fate of pre-existing SMCs in atherosclerotic plaques remain poorly defined.
A. Misra +11 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben +8 more
wiley +1 more source