Results 11 to 20 of about 1,146,198 (394)

Plaque formation and isolation of pure lines with poliomyelitis virus [PDF]

Journal of Experimental Medicine, 1954
Plaques have been produced with the three types of poliomyelitis viruses on monolayer tissue cultures of monkey kidney and monkey testis. The number of plaques was proportional to the concentration of the virus.
Dulbecco, R., Vogt, Marguerite
core   +4 more sources

Inflammation during the life cycle of the atherosclerotic plaque.

Cardiovascular Research, 2021
Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed, inflammatory mediators likely link many traditional and emerging risk factors with atherogenesis.
P. Libby
semanticscholar   +1 more source

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

Nature Communications, 2021
The role of microglia cells in Alzheimer’s disease (AD) is well recognized, however their molecular and functional diversity remain unclear. Here, we isolated amyloid plaque-containing (using labelling with methoxy-XO4, XO4+) and non-containing (XO4 ...
Alexandra Grubman, Xin Yi Choo, Gabriel Chew, John F. Ouyang, Gui-zhi Sun, N. Croft, F. Rossello, R. Simmons, S. Buckberry, Dulce Vargas Landin, Jahnvi Pflueger, Teresa H Vandekolk, Zehra C. Abay, Yichen Zhou, Xiaodong Liu, Joseph Chen, M. Larcombe, J. Haynes, C. Mclean, Sarah Williams, S. Chai, Trevor Wilson, R. Lister, C. Pouton, A. Purcell, O. Rackham, E. Petretto, J. Polo   +27 more
semanticscholar   +1 more source

The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome

Acta Neuropathologica Communications, 2022
Amyloid plaques contain many proteins in addition to beta amyloid (Aβ). Previous studies examining plaque-associated proteins have shown these additional proteins are important; they provide insight into the factors that drive amyloid plaque development ...
Eleanor Drummond, Tomas Kavanagh, Geoffrey Pires, Mitchell Martá-Ariza, E. Kanshin, Shruti D Nayak, A. Faustin, Valentin Berdah, B. Ueberheide, T. Wisniewski   +9 more
semanticscholar   +1 more source

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Journal of Neuroscience, 2006
Mutations in the genes for amyloid precursor protein (APP) and presenilins (PS1, PS2) increase production of β-amyloid 42 (Aβ42) and cause familial Alzheimer's disease (FAD).
Holly Oakley, Sarah L. Cole, Sreemathi Logan, Erika Maus, Peizhen Shao, J. Craft, Angela L. Guillozet-Bongaarts, M. Ohno, J. Disterhoft, L. V. Van Eldik, R. Berry, R. Vassar   +11 more
semanticscholar   +1 more source

Clinical Molecular Imaging for Atherosclerotic Plaque

Journal of Imaging, 2021
Atherosclerosis is a well-known disease leading to cardiovascular events, including myocardial infarction and ischemic stroke. These conditions lead to a high mortality rate, which explains the interest in their prevention, early detection, and treatment.
Anton Kondakov, Vladimir Lelyuk
doaj   +1 more source

Extracalvarial Porocarcinoma -A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2021
Eccrine Porocarcinoma (EPC) is a very rare malignant neoplasm of skin. It usually emerges from the ductal parts of sweat glands. It is seen mostly between the age group of 60 to 80 years with a female preponderance.
SATYAM SINGH, SUHAS JAJOO, ABHISHEK VAIJNATH CHAUDHARI, SAMARTH SHUKLA, SOURYA ACHARYA   +4 more
doaj   +1 more source

Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stage [PDF]

, 2019
Dental calculus, calcified oral plaque biofilm, contains microbial and host biomolecules that can be used to study historic microbiome communities and host responses.
CJ Adler, C Warinner, C Warinner, S Buckley, IM Velsko, J Hendy, ID Mandel, C Warinner, C Walker, V Zijnge, P Ramberg, D Belstrøm, PE Kolenbrander, WG Wade, SS Socransky, IM Velsko, SC Holt, M Umeda, BH Mullally, JW Lee, IM Velsko, LM Shaddox, AW Aruni, KL Cross, L Albayrak, S Yost, VM Barnes, JL Ebersole, S Yost, P Jorth, A Basic, RR Jersie-Christensen, T Imamura, LS Weyrich, AA Ribeiro, EL Gross, A Simón-Soro, Zachary D. Moye, O Manor, SM Dabdoub, D Belstrøm, RC Page, S Hillson, A Ogden, S Brooks, JL Buckberry, D Ferembach, CO Lovejoy, TW Phenice, LAF Frantz, P Skoglund, P Skoglund, M. Meyer, A Ginolhac, H Jónsson, A Peltzer, M Schubert, H Li, H Li, M Meyer, D Knights, N Segata, DT Truong, DH Parks, DH Parks, M Bastian, R Overbeek, DH Huson, MC Chambers, FE Dewhirst   +69 more
core   +4 more sources

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Circulation Research, 2020
Supplemental Digital Content is available in the text. Rationale: Atherosclerotic lesions are known for their cellular heterogeneity, yet the molecular complexity within the cells of human plaques has not been fully assessed. Objective: Using single-cell
M. Depuydt, K. Prange, L. Slenders, T. Örd, D. Elbersen, Arjan Boltjes, S. D. de Jager, F. Asselbergs, G. D. de Borst, E. Aavik, T. Lönnberg, E. Lutgens, C. Glass, H. D. den Ruijter, M. Kaikkonen, I. Bot, B. Slütter, S. W. van der Laan, S. Yla-Herttuala, M. Mokry, J. Kuiper, M. D. de Winther, G. Pasterkamp   +22 more
semanticscholar   +1 more source

The Correlation Between Collagen Types and Ultrasound Feature Score in Evaluating the Vulnerability of Carotid Artery Plaque

Frontiers in Cardiovascular Medicine, 2021
Objectives: To investigate whether ultrasound score has clinical value in identifying carotid artery-vulnerable plaque and the impacts of collagen distribution on the stability of plaque.Materials and Methods: Standard carotid artery ultrasound ...
Ruijun Han, Ruijun Han, Yanhong Yan, Yafang Ding, Yabo Huang, Peng Zhou, Pinjing Hui   +6 more
doaj   +1 more source