Secukinumab in plaque psoriasis--results of two phase 3 trials.
New England Journal of Medicine, 2014 BACKGROUND Interleukin-17A is considered to be central to the pathogenesis of psoriasis. We evaluated secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe plaque psoriasis.
R. Langley +19 more
semanticscholar +1 more source
Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study. [PDF]
, 2018 Despite reducing progression and promoting regression of coronary atherosclerosis, statin therapy does not fully address residual cardiovascular (CV) risk.
Brent Muhlestein, J +5 more
core +2 more sources
Plaque regression and plaque stabilisation in cardiovascular diseases
Indian Journal of Endocrinology and Metabolism, 2013 Atherosclerosis is characterized by formation of plaques on the inner walls of arteries that threatens to become the leading cause of death worldwide via its sequelae of myocardial infarction and stroke. Endothelial dysfunction leads to cholesterol uptake and accumulation of inflammatory markers within the plaque.
Tarun Dave +3 more
openaire +3 more sources
High Zn content of Randall's plaque: A μ-X-ray fluorescence investigation [PDF]
, 2011 Kidney stone disease, or nephrolithiasis, is a common ailment. Among the different risk factors usually associated with nephrolithiasis are dehydration, metabolic defects (especially with regard to calcium and oxalate).
Albouy, Pierre-Antoine +7 more
core +2 more sources
Percent atheroma volume: Optimal variable to report whole-heart atherosclerotic plaque burden with coronary CTA, the PARADIGM study. [PDF]
, 2020 BACKGROUND AND AIMS:Different methodologies to report whole-heart atherosclerotic plaque on coronary computed tomography angiography (CCTA) have been utilized.
Al Hussein, Omar +37 more
core +2 more sources
Résultats de la chirurgie laparoscopique pour la hernie de l'aine: l'expérience Tunisienne
The Pan African Medical Journal, 2018 La hernie de l'aine de l'adulte reste une affection fréquente en chirurgie digestive. De nombreuses techniques de réparation ont été décrites à ce jour dont les procédés laparoscopiques.
Houcine Maghrebi +9 more
doaj +1 more source
Neuroimaging of the Vulnerable Plaque [PDF]
Current Vascular Pharmacology, 2015 Plaque vulnerability due to inflammation has been shown to be a participating factor in the degenerative process in the arterial wall that contributes to stenosis and embolism. This is believed to have an important role to play also in the genesis of stroke or cerebrovascular diseases.
Lövblad, Karl-Olof +7 more
openaire +4 more sources
Oral microbiota carriage in patients with multibracket appliance in relation to the quality of oral hygiene [PDF]
, 2016 Background: The present study aimed to investigate the prevalence of oral microbiota (Candida species (spp.), Streptococcus mutans, and Lactobacilli) in patients with multibracket (MB) appliances in relation to the quality of oral hygiene.
Eichenauer, Johanna +3 more
core +2 more sources
Circulation Research, 2019 The mechanisms that underlie superficial erosion, a cause of coronary thrombosis distinct from plaque rupture, have garnered recent interest. In an era of improved control of traditional risk factors, such as LDL (low-density lipoprotein), plaque erosion
P. Libby +3 more
semanticscholar +1 more source
MicroRNAs in the Atherosclerotic Plaque [PDF]
Clinical Chemistry, 2013 BACKGROUND MicroRNAs (miRNA, miR) are noncoding RNAs that regulate gene expression by hindering translation. miRNA expression profiles have been shown to differ in vivo and in vitro in many cellular processes associated with cardiovascular diseases (CVDs).
Emma Raitoharju +2 more
openaire +2 more sources