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Acute coronary syndromes: mechanisms, challenges, and new opportunities. [PDF]

Eur Heart J
Kraler S, Mueller C, Libby P, Bhatt DL.
europepmc   +1 more source

Impact of Anabolic-Androgenic Steroids on Coronary Artery Disease: Insights From Optical Coherence Tomography. [PDF]

JACC Case Rep
Abdelsamie AH, Abdelhadi HO.
europepmc   +1 more source

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Characteristics of carotid atherosclerosis in patients with plaque erosion

Journal of Thrombosis and Thrombolysis, 2021
Plaque erosion (PE) is a major underlying mechanism of acute coronary syndrome (ACS). Patients with PE may have less systemic atherosclerosis. We aimed to clarify the status of carotid atherosclerosis in patients with PE. A total of 115 consecutive patients with ACS who underwent optical coherence tomography (OCT) imaging of the culprit lesion were ...
Ayami Kato, Y. Minami, K. Asakura, M. Katamine, A. Katsura, Y. Muramatsu, Toshimitsu Sato, Ryota Kakizaki, T. Hashimoto, K. Meguro, T. Shimohama, J. Ako   +11 more
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Risk Factors Favoring Plaque Erosion.

Current Atherosclerosis Reports
Plaque erosion is the second leading cause of coronary thrombosis following plaque rupture and represents a key pathophysiological process underlying acute coronary syndromes that can culminate in sudden coronary death. While the precise mechanisms and risk factors driving plaque rupture are well-established, those for erosion have only recently been ...
Tomoyo Hamana, Palak Shah, Alyssa Grogan, Rika Kawakami, Desiree Williams, Keisha Medina Diaz, R. Virmani, A. Finn   +7 more
semanticscholar   +3 more sources

Inflammation in plaque erosion and rupture

Nature Reviews Cardiology, 2021
K. Huynh
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Toll-like receptor 2, hyaluronan, and neutrophils play a key role in plaque erosion: the OPTICO-ACS study.

European Heart Journal, 2023
BACKGROUND AND AIMS In one-third of patients with acute coronary syndrome (ACS), thrombosis occurs despite an intact fibrous cap (IFC) (IFC-ACS, 'plaque erosion').
D. Meteva, R. Vinci, C. Seppelt, Y. Abdelwahed, D. Pedicino, Gregor Nelles, C. Skurk, A. Haghikia, Ursula Rauch-Kröhnert, T. Gerhardt, E. Straessler, Yingjie Zhao, Felix Golla, M. Joner, H. Rai, A. Kratzer, H. G. Arnal, G. Liuzzo, J. Klotsche, F. Crea, U. Landmesser, D. Leistner, N. Kränkel   +22 more
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Plaque rupture and erosion

2021
Despite improvement in the treatment, prevention, and risk factor management of atherosclerosis, the most frequent cause of death globally remains coronary artery disease. Therefore, it is essential to understand the underlying mechanisms involved in the manifestation of acute coronary syndromes, sudden cardiac death, or stable ischaemic heart disease.
Hiroyoshi Mori, Sho Torii, Renu Virmani
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Plaque Rupture and Plaque Erosion

Thrombosis and Haemostasis, 1999
SummaryThere are multiple substrates for coronary thrombosis overlying an atherosclerotic plaque. The most common, plaque rupture, consists of an interruption of a thin fibrous cap overlying a lipid rich core. Plaque rupture is a result of macrophage infiltration and matrix degradation, is often seen in calcified plaques, and is highly associated with ...
Renu Virmani, Allen P. Burke, Andrew Farb   +2 more
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Erosive Plaque on Scrotum

JAMA, 2014
A61-year-oldmanpresentswith apainlessplaqueon the right sideof his scrotum; theplaque first appeared 1.5yearsagoandhasbeenslowly enlarging since. The patient reports experiencing no fevers or chills since the plaque developed. On examination the bright reddish, irregularly shaped plaquemeasures4.0 × 1.5 cmandhas erosions on the surface (Figure 1).
Jun Li, Heyi Zheng
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