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Role of mechanical stress and neutrophils in the pathogenesis of plaque erosion.
Atherosclerosis, 2020Mechanical stress is a well-recognized driver of plaque rupture. Likewise, investigating the role of mechanical forces in plaque erosion has recently begun to provide some important insights, yet the knowledge is by far less advanced. The most significant example is that of shear stress, which has early been proposed as a possible driver for focal ...
Grégory Franck
semanticscholar +4 more sources
European Heart Journal, 2023
BACKGROUND AND AIMS In one-third of patients with acute coronary syndrome (ACS), thrombosis occurs despite an intact fibrous cap (IFC) (IFC-ACS, 'plaque erosion').
D. Meteva +22 more
semanticscholar +1 more source
BACKGROUND AND AIMS In one-third of patients with acute coronary syndrome (ACS), thrombosis occurs despite an intact fibrous cap (IFC) (IFC-ACS, 'plaque erosion').
D. Meteva +22 more
semanticscholar +1 more source
Plaque Rupture and Plaque Erosion
Thrombosis and Haemostasis, 1999SummaryThere are multiple substrates for coronary thrombosis overlying an atherosclerotic plaque. The most common, plaque rupture, consists of an interruption of a thin fibrous cap overlying a lipid rich core. Plaque rupture is a result of macrophage infiltration and matrix degradation, is often seen in calcified plaques, and is highly associated with ...
Renu Virmani +2 more
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2021
Despite improvement in the treatment, prevention, and risk factor management of atherosclerosis, the most frequent cause of death globally remains coronary artery disease. Therefore, it is essential to understand the underlying mechanisms involved in the manifestation of acute coronary syndromes, sudden cardiac death, or stable ischaemic heart disease.
Hiroyoshi Mori, Sho Torii, Renu Virmani
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Despite improvement in the treatment, prevention, and risk factor management of atherosclerosis, the most frequent cause of death globally remains coronary artery disease. Therefore, it is essential to understand the underlying mechanisms involved in the manifestation of acute coronary syndromes, sudden cardiac death, or stable ischaemic heart disease.
Hiroyoshi Mori, Sho Torii, Renu Virmani
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JAMA, 2014
A61-year-oldmanpresentswith apainlessplaqueon the right sideof his scrotum; theplaque first appeared 1.5yearsagoandhasbeenslowly enlarging since. The patient reports experiencing no fevers or chills since the plaque developed. On examination the bright reddish, irregularly shaped plaquemeasures4.0 × 1.5 cmandhas erosions on the surface (Figure 1).
Jun Li, Heyi Zheng
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A61-year-oldmanpresentswith apainlessplaqueon the right sideof his scrotum; theplaque first appeared 1.5yearsagoandhasbeenslowly enlarging since. The patient reports experiencing no fevers or chills since the plaque developed. On examination the bright reddish, irregularly shaped plaquemeasures4.0 × 1.5 cmandhas erosions on the surface (Figure 1).
Jun Li, Heyi Zheng
openaire +3 more sources
Current Opinion in Cardiology, 2021
Purpose of review The current systematic review aims to provide novel insights into the distinct pathological features of acute coronary syndrome (ACS) with intact fibrous cap, also known as ‘plaque erosion’.
D. Meteva +3 more
semanticscholar +1 more source
Purpose of review The current systematic review aims to provide novel insights into the distinct pathological features of acute coronary syndrome (ACS) with intact fibrous cap, also known as ‘plaque erosion’.
D. Meteva +3 more
semanticscholar +1 more source
Endothelial erosion of plaques as a substrate for coronary thrombosis
Thrombosis and Haemostasis, 2016SummaryMyocardial infarction is a prevalent, life-threatening consequence of athero-thrombosis. Post-mortem histology and intravascular imaging in live patients have shown that approximately one third of myocardial infarctions are caused by a thrombus overlying an intact, non-ruptured atherosclerotic plaque.
White, Steve +2 more
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Erosive plaques on the dorsal surfaces of the hands
Journal of the American Academy of Dermatology, 2012From Yo D M Fund Conf Repr D An otherwise healthy 58-year-old woman presents with a 10-day history of ulcers on the dorsal surfaces of both hands. The initial lesion, an expanding pustule, became bullous and erosive. She subsequently developed large bullous hemorrhagic plaques on both forearms.
Ali Jabbari +4 more
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Angiographic features of patients with coronary plaque erosion
International Journal of Cardiology, 2019Although an in vivo diagnosis of coronary plaque erosion has become possible by optical coherence tomography (OCT), angiographic characteristics of erosion have not been studied. The aim of this study was to investigate the angiographic features of plaque erosion in patients with non-ST elevation acute coronary syndromes (NSTE-ACS).Patients with NSTE ...
Ik-Kyung Jang +11 more
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Pathophysiology of coronary thrombosis: Role of plaque rupture and plaque erosion
Progress in Cardiovascular Diseases, 2002Coronary artery disease is the leading cause of death in much of the western world. Atherosclerotic plaques in the coronary arteries contribute to luminal obstruction leading to myocardial ischemia; however, abrupt coronary artery occlusion most frequently results from superimposition of a thrombus on a disrupted plaque, leading to the most serious ...
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