Results 61 to 70 of about 13,822 (240)
Pathophysiology of Acute Coronary Syndromes—Diagnostic and Treatment Considerations
Life, 2023 Coronary artery disease and acute coronary syndromes are accountable for significant morbidity and mortality, despite the preventive measures and technological advancements in their management. Thus, it is mandatory to further explore the pathophysiology
Panagiotis Theofilis +4 more
doaj +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen +10 more
wiley +1 more source
Combined Use of Multiple Intravascular Imaging Techniques in Acute Coronary Syndrome
Frontiers in Cardiovascular Medicine, 2022 Recent advances in intravascular imaging techniques have made it possible to assess the culprit lesions of acute coronary syndrome (ACS) in the clinical setting.
Takashi Kubo +9 more
doaj +1 more source
Learning beyond the lab: A gamified approach to anatomy education in a museum‐based experience
Anatomical Sciences Education, EarlyView.Abstract Anatomy education, traditionally rooted in descriptive instruction and cadaveric dissection, is undergoing a significant transformation through the integration of educational technologies and contemporary pedagogical strategies. Among these, active learning methodologies, such as gamified‐based learning, have emerged as approaches designed to ...
Wendell Nunes da Silva +3 more
wiley +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Atherothrombosis in Acute Coronary Syndromes—From Mechanistic Insights to Targeted Therapies
Cells, 2021 The atherothrombotic substrates for acute coronary syndromes (ACS) consist of plaque ruptures, erosions and calcified nodules, while the non-atherothrombotic etiologies, such as spontaneous coronary artery dissection, coronary artery spasm and coronary ...
Chinmay Khandkar +4 more
doaj +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Heavily calcified coronary lesions remain a major challenge in percutaneous coronary intervention (PCI), often limiting the effectiveness of intravascular lithotripsy (IVL). We report a five‐case series in which IVL failed to achieve adequate lesion modification but was successfully augmented by the addition of one or more buddy wires.
Alfredo Marchese +5 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT We present a 66‐year‐old undergoing ostial‐to‐mid right coronary artery (RCA) percutaneous coronary intervention (PCI) lesion proximal to an existing stent in the mid‐to‐distal segment. The patient underwent PCI, with intravascular imaging using the Novasight Hybrid IVUS OCT (Conavi, Toronto, CA) which revealed a proximal edge dissection and ...
Natali Sorajja +3 more
wiley +1 more source