Results 81 to 90 of about 13,822 (240)

Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul   +3 more
wiley   +1 more source

Menopause hormone therapy in women with cardiovascular risk factors or established ischemic heart disease: A joint FIGO and WHF position paper

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto   +9 more
wiley   +1 more source

Emergence of Plaque Erosion as an Important Clinical Entity

open access: yesJACC: Cardiovascular Imaging, 2015
Most physicians believe that acute coronary syndromes (ACS) are due to coronary artery thrombosis resulting from plaque rupture of a metabolically active inflamed lesion characterized by a thin fibrous cap (thin-cap fibroatheroma [TCFA]), overlying a large necrotic core containing ...
Stone, Gregg W., Narula, Jagat
openaire   +2 more sources

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source

Asymptomatic oral plaques and erosion

open access: yesCleveland Clinic Journal of Medicine, 2023
Li-Wen, Zhang   +3 more
openaire   +2 more sources

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

open access: yesiNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin   +10 more
wiley   +1 more source

Smoking effects on root coverage outcomes between 3 and 12 months: A prospective cohort study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the impact of smoking on root coverage outcomes, comparing healing responses at 3–12 months following coronally advanced flap with a connective tissue graft (CAF+CTG). Methods This prospective cohort study included 27 participants (13 smokers, 14 non‐smokers) who required root coverage for a single Cairo
Hande Has‐Elci   +6 more
wiley   +1 more source

Zinc‐stabilized stannous fluoride modulates the periodontal microbiome, reducing Fusobacteria, key Gram‐negative species, and overall inflammation within an experimental gingivitis clinical trial

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the effects of a dentifrice containing stannous fluoride stabilized with zinc phosphate on subgingival microbiome composition and clinical inflammation during experimental gingivitis, compared with a sodium fluoride control. Methods This investigation was conducted as a secondary analysis of a randomized,
Kristopher A. Kerns   +8 more
wiley   +1 more source

Double‐VISTA technique with connective tissue graft or acellular dermal matrix for treating multiple recessions associated with non‐carious cervical lesions: A retrospective study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This retrospective study evaluated whether clinical outcomes differed between connective tissue graft (CTG) and allogeneic solvent‐dehydrated acellular dermal matrix (ADM) for treating multiple gingival recessions associated with non‐carious cervical lesions (NCCLs) using partial restoration and the double‐vestibular incision ...
Guo‐Hao Lin   +6 more
wiley   +1 more source

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