The relation between atherosclerosis plaque composition and plaque rupture [PDF]
Background: Intima, media, and adventitia are three layers of arteries. They have different structures and different mechanical properties. Damage to intima layer of arteries leads to an inflammatory response, which is usually the reason for ...
Parto Babaniamansour+3 more
doaj +6 more sources
Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis [PDF]
Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stress exerting this disrupting force.
Andrea Milzi+6 more
doaj +3 more sources
Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis [PDF]
Atherosclerosis is a progressive vascular wall inflammatory disease, and the rupture of atherosclerotic vulnerable plaques is the leading cause of morbidity and mortality worldwide.
Peng Nie+4 more
doaj +2 more sources
Identification of Carotid Artery Microstructure and Plaque Rupture Using C-Arm Cone-Beam CT: A Case Report [PDF]
C-arm cone-beam computed tomography (CBCT) offers a high imaging resolution with a wide range of contrast to visualize vessels, soft tissue, and bone.
Jia Dong+15 more
doaj +2 more sources
Association of Neutrophil to Lymphocyte Ratio With Plaque Rupture in Acute Coronary Syndrome Patients With Only Intermediate Coronary Artery Lesions Assessed by Optical Coherence Tomography [PDF]
ObjectivesPlaque vulnerability and rupture rather than plaque size are the major cause of clinical events in patients with intermediate coronary lesions.
Jintong Jiang+6 more
doaj +2 more sources
Plaque Structural Stress: Detection, Determinants and Role in Atherosclerotic Plaque Rupture and Progression [PDF]
Atherosclerosis remains a major cause of death worldwide, with most myocardial infarctions being due to rupture or erosion of coronary plaques. Although several imaging modalities can identify features that confer risk, major adverse cardiovascular event
Sophie Z. Gu, Martin R. Bennett
doaj +2 more sources
Mechanisms of Plaque Formation and Rupture [PDF]
Atherosclerosis causes clinical disease through luminal narrowing or by precipitating thrombi that obstruct blood flow to the heart (coronary heart disease), brain (ischemic stroke), or lower extremities (peripheral vascular disease). The most common of these manifestations is coronary heart disease, including stable angina pectoris and the acute ...
Bentzon, Jacob Fog+3 more
openaire +4 more sources
Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women. [PDF]
Although plaque erosion causes approximately 40% of all coronary thrombi and disproportionally affects women more than men, its mechanism is not well understood.
Ian C Campbell+7 more
doaj +2 more sources
Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture. [PDF]
Supplemental Digital Content is available in the text. Rationale: Plaque rupture is the proximate cause of most myocardial infarctions and many strokes. However, the molecular mechanisms that precipitate plaque rupture are unknown. Objective: By applying
Vaisar T+12 more
europepmc +2 more sources
Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. [PDF]
BackgroundRupture of atherosclerotic plaques is probably the most important mechanism underlying the sudden onset of acute coronary syndromes. Macrophages may release lytic enzymes that degrade the fibrous cap and therefore produce rupture of the ...
Pedro R. Moreno+5 more
openalex +2 more sources