Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture. [PDF]
Circ Res, 2020 Supplemental Digital Content is available in the text. Rationale: Plaque rupture is the proximate cause of most myocardial infarctions and many strokes. However, the molecular mechanisms that precipitate plaque rupture are unknown. Objective: By applying
Vaisar T +12 more
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Biomechanics and inflammation in atherosclerotic plaque erosion and plaque rupture: implications for cardiovascular events in women. [PDF]
PLoS ONE, 2014 Although plaque erosion causes approximately 40% of all coronary thrombi and disproportionally affects women more than men, its mechanism is not well understood.
Ian C Campbell +7 more
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Effect of 1,5-anhydroglucitol levels on culprit plaque rupture in diabetic patients with acute coronary syndrome [PDF]
Cardiovascular Diabetology, 2020 Background Postprandial hyperglycemia was reported to play a key role in established risk factors of coronary artery diseases (CAD) and cardiovascular events.
Gong Su +6 more
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Visualization of Vulnerable Coronary Plaque and Prevention of Plaque Rupture. [PDF]
Juntendo Iji ZasshiIn daily clinical practice, assessing anatomical findings and the presence or absence of ischemia is pivotal for determining the need for percutaneous coronary intervention. However, concurrently, comprehending vulnerability can greatly assist in predicting future cardiovascular events and formulating preventive strategies for individual patients. This
Fukase T, Dohi T.
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Imaging Atherosclerosis and Risk of Plaque Rupture [PDF]
Current Atherosclerosis Reports, 2013 Atherosclerosis imaging strategies can delineate characteristics of plaques at risk of rupture and thrombosis. Structural plaque imaging identifies high-risk plaque features, including lipid pools, thin fibrous caps, and intraplaque hemorrhage. New molecular imaging techniques complement structural imaging approaches by illuminating important features ...
E. Osborn, F. Jaffer
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Macrophage Infiltration in Acute Coronary Syndromes: Implications for Plaque Rupture [PDF]
Circulation, 1994 P. Moreno +5 more
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Thrombosis formation on atherosclerotic lesions and plaque rupture
Journal of Internal Medicine, 2014 Maria Borrell-pages
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Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction
Frontiers in Immunology, 2022 BackgroundAcute myocardial infarction (AMI) can occur in patients with atherosclerotic disease, with or without plaque rupture. Previous studies have indicated a set of immune responses to plaque rupture.
Jun Qian +14 more
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Platelet biology and function: plaque erosion vs. rupture
European Heart Journal, 2023 The leading cause of heart disease in developed countries is coronary atherosclerosis, which is not simply a result of ageing but a chronic inflammatory process that can lead to acute clinical events upon atherosclerotic plaque rupture or erosion and ...
Constance C F M J Baaten +4 more
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Cardiovascular Research, 2020 AIMS To investigate local haemodynamics in the setting of acute coronary plaque rupture and erosion. METHODS AND RESULTS Intracoronary optical coherence tomography performed in 37 patients with acute coronary syndromes caused by plaque rupture (n = 19)
V. Thondapu +14 more
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