Results 31 to 40 of about 700,142 (373)

Morphological and Stress Vulnerability Indices for Human Coronary Plaques and Their Correlations with Cap Thickness and Lipid Percent: An IVUS-Based Fluid-Structure Interaction Multi-patient Study. [PDF]

open access: yesPLoS Computational Biology, 2015
Plaque vulnerability, defined as the likelihood that a plaque would rupture, is difficult to quantify due to lack of in vivo plaque rupture data. Morphological and stress-based plaque vulnerability indices were introduced as alternatives to obtain ...
Liang Wang   +9 more
doaj   +1 more source

Macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development [PDF]

open access: yesBull Math Biol 85, 37 (2023), 2022
Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment ...
arxiv   +1 more source

Plasma Trimethylamine N-Oxide as a Novel Biomarker for Plaque Rupture in Patients With ST-Segment–Elevation Myocardial Infarction

open access: yesCirculation. Cardiovascular Interventions, 2019
Background Trimethylamine N-oxide (TMAO) is reported to promote the pathogenesis of atherosclerosis and be associated with cardiovascular events risk.
Yu Tan   +15 more
semanticscholar   +1 more source

The tandem stenosis mouse model: Towards understanding, imaging, and preventing atherosclerotic plaque instability and rupture

open access: yesBritish Journal of Pharmacology, 2020
The rupture of unstable atherosclerotic plaques is the major cause of cardiovascular mortality and morbidity. Despite significant limitations in our understanding and ability to identify unstable plaque pathology and prevent plaque rupture, most ...
J. Noonan, A. Bobik, K. Peter
semanticscholar   +1 more source

Analysis of atherosclerotic plaque distribution in the carotid artery

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1272-1276, December 2022., 2022
Abstract Background The present study was designed to investigate the hypothesis that the outer wall at the carotid bifurcation is the most common area of atherosclerotic plaque deposition due to the low shear stress. Hypothesis We hypothesized that the most common site of arteriosclerosis in carotid arteries is different in the early and late stages ...
Shin‐Seok Yang   +2 more
wiley   +1 more source

Importance of inflammation in arteriosclerotic plaque destabilization and rupture [PDF]

open access: yesVojnosanitetski Pregled, 2005
Introduction. Although Rudolf Virchow considered arteriosclerosis an inflammatory disease in his book Cellular Pathology published in 1858, the opinion that it was a degenerative arterial disease as a civilization disease prevailed.
Tatić Vujadin   +4 more
doaj   +1 more source

Antibacterial effects of natural compounds on biofilm formation of Streptococcus mutans

open access: yesClinical and Experimental Dental Research, Volume 8, Issue 6, Page 1426-1433, December 2022., 2022
Abstract Streptococcus mutans is the main cariogenic pathogen in the oral cavity, considered to contribute toward oral diseases. S. mutans is predominantly entrapped in plaque biofilms. Objectives In this study, we surveyed the antibacterial activity of natural compounds in terms of the biofilm production of S. mutans. Material and Methods We extracted
Farideh Kamarehei   +2 more
wiley   +1 more source

A novel workflow combining plaque imaging, plaque and plasma proteomics identifies biomarkers of human coronary atherosclerotic plaque disruption

open access: yesClinical Proteomics, 2017
Background Atherosclerotic plaque rupture is the culprit event which underpins most acute vascular syndromes such as acute myocardial infarction. Novel biomarkers of plaque rupture could improve biological understanding and clinical management of ...
Regent Lee   +10 more
doaj   +1 more source

Studying the Factors of Human Carotid Atherosclerotic Plaque Rupture, by Calculating Stress/Strain in the Plaque, Based on CEUS Images: A Numerical Study

open access: yesFrontiers in Neuroinformatics, 2020
Carotid plaque neovascularization is one of the major factors for the classification of vulnerable plaque, but the axial force effects of the pulsatile blood flow on the plaque with neovessel and intraplaque hemorrhage was unclear.
Zhenzhou Li   +7 more
doaj   +1 more source

Mean platelet volume and coronary plaque vulnerability: an optical coherence tomography study in patients with non-ST-elevation acute coronary syndrome

open access: yesBMC Cardiovascular Disorders, 2019
Background The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated.
Jun Wang   +7 more
doaj   +1 more source

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