Results 41 to 50 of about 755,810 (388)
Mechanisms of plaque vulnerability and rupture [PDF]
Journal of the American College of Cardiology, 2003 Rupture of atherosclerotic plaque has been identified as the proximate event in the majority of cases of acute ischemic syndromes. Plaque rupture exposes thrombogenic components of the plaque, activating the clotting cascade and promoting thrombus formation.
openaire +2 more sources
Journal of Biomedical Science, 2009 Background It is widely believed that atherosclerotic plaque rupture and subsequent thrombosis leads to acute coronary events and stroke. However, study of the mechanism and treatment of human plaque rupture is hampered by lack of a suitable animal model.
Jiang Zhi-Xin +2 more
doaj +1 more source
Utility of mass spectrometry for the diagnosis of the unstable coronary plaque. [PDF]
, 2015 Mass spectrometry is a powerful technique that is used to identify unknown compounds, to quantify known materials, and to elucidate the structure and chemical properties of molecules.
Hassan, M, Jacob, SS, Yacoub, MH
core +1 more source
Redox Report, 2016 Atherosclerosis is the main pathophysiological process underlying coronary artery disease (CAD). Acute complications of atherosclerosis, such as myocardial infarction, are caused by the rupture of vulnerable atherosclerotic plaques, which are ...
N. Teng +5 more
semanticscholar +1 more source
Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice [PDF]
, 2016 Background and aims Observational studies show a peak incidence of cardiovascular events after major surgery. For example, the risk of myocardial infarction increases 25-fold early after hip replacement.
Chen +39 more
core +1 more source
Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study. [PDF]
, 2018 Despite reducing progression and promoting regression of coronary atherosclerosis, statin therapy does not fully address residual cardiovascular (CV) risk.
Brent Muhlestein, J +5 more
core +2 more sources
Circulation: Cardiovascular Genetics, 2017 Background— Atherosclerotic plaque rupture is accompanied by an acute decrease in the carotid plaque expression of micro-RNAs (miRs)-221 and miR-222. Circular RNA (circR)-284 is a potential inhibitor of miR-221/miR-222 activity.
Hernan A. Bazan +5 more
semanticscholar +1 more source
Is cadmium exposure associated with the burden, vulnerability and rupture of human atherosclerotic plaques? [PDF]
PLoS ONE, 2015 The general population is exposed to cadmium from food and smoking. Cadmium is a widely spread toxic pollutant that seems to be associated with cardiovascular diseases, although little is known if it contributes to the occurrence of atherosclerotic ...
Göran Bergström +4 more
doaj +1 more source
Application of ex vivo cryo-imaging technique for three-dimensional finite element analysis of atherosclerotic plaque rupture [PDF]
, 2015 PublishedCryo-imaging is an ex vivo vascular imaging modality that acquires serial 2D fluorescence and bright-field images at 20μm increments without sacrifice to tissue morphology.
Abdul-Aziz, Ahmad A. +8 more
core +1 more source
European Heart Journal-Cardiovascular Imaging, 2016 AIMS The prevalence of plaque rupture at the culprit lesion identified by optical coherence tomography (OCT) in different clinical subset of patients undergoing coronary angiography and its clinical predictors remain to be defined.
M. Iannaccone +20 more
semanticscholar +1 more source