Results 161 to 170 of about 2,493,525 (282)

DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice. [PDF]

J Clin Invest, 2023
Herman AB, Tsitsipatis D, Anerillas C, Mazan-Mamczarz K, Carr AE, Gregg JM, Wang M, Zhang J, Michel M, Henry-Smith CA, Harris SC, Munk R, Martindale JL, Piao Y, Fan J, Mattison JA, De S, Abdelmohsen K, Maul RW, Tanaka T, Moore AZ, DeMouth ME, Sidoli S, Ferrucci L, Liu Y, de Cabo R, Lakatta EG, Gorospe M.   +27 more
europepmc   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Interleukin-16 upregulates tissue inhibitor of metalloproteinase 3 to promote atherosclerotic plaque stability. [PDF]

J Transl Med
He H, Ding M, Zhu Y, Jiang T, Dong D, Xu X, Yu W, Ou H.   +7 more
europepmc   +1 more source

Metformin Directly Binds to MMP-9 to Improve Plaque Stability. [PDF]

J Cardiovasc Dev Dis, 2023
Chen X, Wang S, Xu W, Zhao M, Zhang Y, Xiao H.   +5 more
europepmc   +1 more source

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

Advanced NanoBiomed Research, EarlyView.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen, Liwen Zhang, Helen Forgham, Jiayuan Zhu, Xumin Huang, Changkui Fu, Ibrahim Javed, Thomas P. Davis, Ruirui Qiao   +8 more
wiley   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

Impact of inflammatory factors on coronary CT calcification score: correlation with plaque stability and evaluation of diagnostic efficiency. [PDF]

Am J Transl Res
Hao Z, Ma D, Wu Y, Cao J, Wang W.
europepmc   +1 more source

Differential expression of platelet CD147 in moderate altitude conditions: implications for coronary plaque stability assessment. [PDF]

Front Cardiovasc Med
Chen Y, Lu S, Bao CP, Ren Y, Lv J, Wang SJ, Wang LS, Zi RX, Zhang X, Yang LX, Wang Y, Shi YK.   +11 more
europepmc   +1 more source

Erratum: Therapeutic ultrasound combined with microbubbles improves atherosclerotic plaque stability by selectively destroying the intraplaque neovasculature: Erratum. [PDF]

Theranostics, 2023
Li X, Guo S, Xu T, He X, Sun Y, Chen X, Cao S, Si X, Liao W, Liao Y, Han Y, Bin J.   +11 more
europepmc   +1 more source

Atheroprotective Immunity and Interleukin-10 Linked to Reduced Characteristics of Plaque Stability. [PDF]

JACC Basic Transl Sci
Yu Y, Lin S, Pan Y, He N, Wu Y, Ahmed O, Hedin U, Karlsson MCI, Li N, Gisterå A.   +9 more
europepmc   +1 more source