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Intracoronary Cryotherapy for Vulnerable Plaque Stabilization
Cardiology in ReviewAcute coronary syndromes most commonly arise from rupture of biologically vulnerable, rather than hemodynamically severe, coronary plaques. Advances in intravascular and noninvasive imaging techniques, including intravascular ultrasound, optical coherence tomography, near-infrared spectroscopy, and coronary computed tomography angiography, have enabled
Nabel Rajab, Basha +5 more
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[Mechanisms of plaque stabilization].
Herz, 1999Numerous angiographic control regression studies have demonstrated that aggressive reduction of plasma cholesterol significantly reduces the incidence of clinical overt cardiovascular complications, but has almost no effect on the angiographically determined luminal diameter of the coronary arteries.
D, Müller-Wieland +3 more
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Plaque stabilization: the role of lipid lowering
International Journal of Cardiology, 2000The unstable atheroma characteristically has a thin, eccentric fibrous cap and a large necrotic core of lipid and cellular debris. This plaque configuration is particularly unstable because large mechanical stresses develop in the thinnest portions of the fibrosis cap over the lipid pool.
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[Plaque stabilization by LDL apheresis?].
Herz, 1999Vulnerable lipid-rich plaques are often the cause of atherothrombotic events leading to unstable angina and/or to acute myocardial infarction. Consequent long-term LDL-lowering by drugs as shown by the most important intervention studies lead to plaque stabilization as shown by the significant reduction of myocardial reinfarction.
P, Schuff-Werner, V, Schettler
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Cardiovascular Pathology, 2009
Fibrates are peroxisome proliferator-activated receptor alpha (PPARalpha) agonists which modulate many aspects of lipoprotein metabolism and inflammation. They have been recently demonstrated to inhibit in vitro expression of tissue factor (TF), the main initiator of blood coagulation, which probably plays a pivotal role in thrombotic complications ...
Emmanuelle, Jeanpierre +9 more
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Fibrates are peroxisome proliferator-activated receptor alpha (PPARalpha) agonists which modulate many aspects of lipoprotein metabolism and inflammation. They have been recently demonstrated to inhibit in vitro expression of tissue factor (TF), the main initiator of blood coagulation, which probably plays a pivotal role in thrombotic complications ...
Emmanuelle, Jeanpierre +9 more
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Plaque Stability and Carotid Stenting
2009Carotid angioplasty and stenting (CAS) is increasingly being performed for the treatment of severely stenotic carotid disease [1–5]. Despite, this growing acceptance, the recently published data of the Eva-3S trial [6], performed in France, and the SPACE trial [7] in Germany failed to prove superiority of CAS over CEA.
M. Bosiers, K. Deloose, P. Peeters
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MRI plaque tissue characterization and assessment of plaque stability.
Studies in health technology and informatics, 2016This chapter reviews current MRI techniques to differentiate stable versus high risk atherosclerosis and discusses the development of non-invasive MR imaging techniques to characterize atherosclerotic plaques. Tissue specific MR signal features will be described according to histo-pathological evaluation standards and comprehensive imaging protocol for
Chun, Yuan +2 more
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