Results 111 to 120 of about 986,615 (364)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Oxidation of clofibric acid in aqueous solution using a non-thermal plasma discharge or gamma radiation

, 2017
In this work, we study degradation of clofibric acid (CFA) in aqueous solution using either ionizing radiation from a $^{60}$Co source or a non-thermal plasma produced by discharges in the air above the solution.
Ceriani, Elisa, Madureira, Joana, Margaça, Fernanda M. A., Marotta, Ester, Melo, Rita, Paradisi, Cristina, Pinhão, Nuno, Verde, Sandra Cabo   +7 more
core   +1 more source

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]

, 2016
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc, Hagerty, David T, Hyndman, David, Iverson, Cory, Liu, Sha, Manhard, Kimberly, Miner, Jeffrey N, Nanavati, Payal, Quart, Barry, Shen, Zancong, Tan, Philip K, Terkeltaub, Robert, Yeh, Li-Tain   +12 more
core   +2 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Enhanced cement properties through plasma-activated water: Exploring hydration kinetics and microstructural refinement

Journal of Materials Research and Technology
Mitigating carbon emissions while enhancing cement performance has remained a persistent challenge in sustainable construction. Here, we demonstrate a novel approach using argon plasma-activated water (Ar-PAW) to significantly improve cement hydration ...
Sattaya Chaiwithee, Kittiphat Kochchapong, Thaloengsak Keereemasthong, Pornchai Rachtanapun, Kittisak Jantanasakulwong, Jonghwan Suhr, Choncharoen Sawangrat, Pitiwat Wattanachai   +7 more
doaj   +1 more source

Effects of Plasma-Activated Water on Skin Wound Healing in Mice

Microorganisms, 2020
Cold atmospheric plasma (CAP) has been widely used in biomedicine during the last two decades. While direct plasma treatment has been reported to promote wound healing, its application can be uneven and inconvenient.
Dehui Xu, Shuai Wang, Bing Li, Miao Qi, Rui Feng, Qiaosong Li, Hao Zhang, Hailan Chen, Michael G Kong   +8 more
doaj   +1 more source

Application of Thermoresponsive Polymer and Microfluidics to the Development of a Velocity-Dependent Cell-Sorting Microdevice [PDF]

, 2018
3rd Place, Denman Undergraduate Research ForumLow-cost velocity dependent cell sorting in 2D is a currently nonexistent technology for cancer research. The development of such a device would enable further research on the treatment of various deleterious
Fine, Jesse
core  

Expression of plasma prekallikrein mRNA in human nonhepatic tissues and cell lineages suggests special local functions of the enzyme [PDF]

, 1999
At present it is generally accepted that plasma prekallikrein (PPK) is synthesized in the liver and secreted into the bloodstream. Surprisingly, it has recently been shown that PPK mRNA is present also in RNA from the kidney, adrenal gland and placenta ...
Arnhold, Marianne, Fink, Edwin, Hermann, Andrea, Kresse, Hans, Neth, Peter   +4 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Evaluation of Cold Plasma–Activated water “…Enriched Metal…” Cations as an Antifungal Agent for Controlling of Penicillium italicum and Penicillium digitatum Molds

Journal of Food Protection
The utilization of Cold Plasma (CP) technology for decontamination and disinfection has garnered considerable attention across diverse industries. This study aims to investigate the interaction between pH and electrical conductivity (EC) (μS/cm) in Cold ...
Tayebeh Shokohi, Alireza Shahab Lavasani, Farnaz Dastmalchi, Hamed Zarei, Kobra Hajizadeh   +4 more
doaj   +1 more source