Results 151 to 160 of about 4,481,490 (243)
Interrelated effects of aldosterone and plasma potassium on potassium excretion
The interacting effects of aldosterone and plasma potassium concentration on steady-state renal potassium excretion were studied in two groups of chronically adrenalectomized dogs.
A. W. Paulsen, D. B. Young
core +1 more source
ABSTRACT Adrenocortical tumors are infrequent neoplasms, ranging from benign adenomas to aggressive carcinomas. They usually have an unspecific clinical presentation, thus being a challenge in diagnosis and treatment. The following case report discusses the management of a large, non‐functional adrenocortical tumor with histologically aggressive ...
Jawad Khan +8 more
wiley +1 more source
An elevated CHG index is significantly associated with new‐onset hypertension, particularly among males or individuals with abnormal glucose metabolism. ABSTRACT Background Hypertension is a major global public health issue, and the continuous search for new biomarkers to optimize risk stratification is crucial.
Huabin He, Jianhai Chen
wiley +1 more source
Aldosterone-Producing Adenomas
Aldosterone-producing adenomas (APA) are more common than initially anticipated. APA cause primary aldosteronism (PA), which affect 3-10% of the hypertensive population.
Åkerström, Tobias, +5 more
core +1 more source
Identification of a Glycosylation‐Related Gene Prognostic Signature for Non–Small Cell Lung Cancer
A ten‐glycosylation‐related‐gene (GRG) prognostic signature for non‐small cell lung cancer (NSCLC) was constructed using TCGA data. Differentially expressed GRGs were screened and refined by Cox and LASSO regression. The ten‐gene signature (including ADAMTS15, PCSK9, MUC2, and B3GNT3) stratified patients into high‐ and low‐risk groups with distinct ...
Qingtao Zhao +2 more
wiley +1 more source
Hypocortisolaemia with gastrointestinal haemorrhage in a young cat
Abstract An 8‐month‐old, female, spayed domestic shorthair presented with a 1‐week history of lethargy and anorexia. On admission, the cat had severe hypoglycaemia, and hypovolaemic and distributive shock were suspected. Mucosal defects identified by ultrasonography were suggestive of gastrointestinal ulceration.
Victoria J. Skinner +2 more
wiley +1 more source
Klotho Deficiency Impairs Distal Potassium Homeostasis Through mTORC1‐Dependent Suppression of ROMK
ABSTRACT Aim Hyperkalemia is prevalent in the elderly, and underlying molecular mechanisms remain incompletely understood. We hypothesized that Klotho deficiency, a feature of aging, impairs renal potassium homeostasis and contributes to hyperkalemia. Methods Klotho heterozygous knockout (KLhet) mice, characterized by reduced Klotho levels, were used ...
Wakako Kawarazaki +6 more
wiley +1 more source
Vitamin D: Physiology, Pharmacology and Clinical Evidence for Supplementation—A Narrative Review
ABSTRACT Vitamin D is a nutrient and prohormone obtained from diet and supplements and synthesized in the skin. It is essential for calcium and phosphate homeostasis and skeletal health and influences multiple extra‐skeletal processes, yet deficiency remains common worldwide.
Jyrki K. Virtanen
wiley +1 more source

