Results 131 to 140 of about 636,644 (329)

Advances in blood biomarkers for Alzheimer disease (AD): A review

Kaohsiung Journal of Medical Sciences
Alzheimer disease (AD) and Alzheimer Disease and Related Dementias (AD/ADRD) are growing public health challenges globally affecting millions of older adults, necessitating concerted efforts to advance our understanding and management of these conditions.
Araya Dimtsu Assfaw, Suzanne E Schindler, John C Morris   +2 more
doaj   +1 more source

Temporal and Severity-Dependent Alterations in Plasma Extracellular Vesicle Profiles Following Spinal Cord Injury

Cells
Spinal cord injury (SCI) triggers both local and systemic pathological responses that evolve over time and differ with injury severity. Small extracellular vesicles (sEVs), known mediators of intercellular communication, may serve as biomarkers ...
Jamie Cooper, Scott Tait Airey, Eric Patino, Theo Andriot, Mousumi Ghosh, Damien D. Pearse   +5 more
doaj   +1 more source

Potential osteomyelitis biomarkers identified by plasma metabolome analysis in mice [PDF]

, 2020
Norihiro Isogai, Yuta Shiono, Tetsuya Kuramoto, Kenji Yoshioka, Hiroko Ishihama, Haruki Funao, Masaya Nakamura, Morio Matsumoto, Ken Ishii   +8 more
openalex   +1 more source

Plasma miRNA Biomarker Signatures in Parkinsonian Syndromes

Molecular Neurobiology
Abstract Diagnosing atypical parkinsonian syndromes (APS) remains challenging due to overlapping clinical features and limited diagnostic tools. Brain-enriched microRNAs (miRNAs), which regulate neuronal development and function, are detectable in plasma and could serve as molecular biomarkers.
Stylianos Ravanidis, Anastasia Bougea, Christos Koros, Athina-Maria Simitsi, Panagiotis Kokotis, Leonidas Stefanis, Epaminondas Doxakis   +6 more
openaire   +2 more sources

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Plasma proteomic profiling of bacterial cold water disease-resistant and -susceptible rainbow trout lines and biomarker discovery [PDF]

, 2023
Gregory D. Wiens, David Marancik, Christopher C. Chadwick, Keira Osbourn, Andrea L. Reid, Timothy D. Leeds   +5 more
openalex   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

High Plasma Levels of sTNF-R1 and CCL11 Are Related to CD4+ T-Cells Fall in Human Immunodeficiency Virus Elite Controllers With a Sustained Virologic Control

Frontiers in Immunology, 2018
Our aim was to analyze the relationship between plasma inflammatory biomarkers and CD4+ T-cells evolution in human immunodeficiency virus (HIV) elite controllers (HIV-ECs) with a suppressed viremia.
Mónica Gutiérrez-Rivas, María Ángeles Jiménez-Sousa, Norma Rallón, Norma Rallón, José Luis Jiménez, José Luis Jiménez, Clara Restrepo, Clara Restrepo, Agathe León, Marta Montero-Alonso, Juan González-García, María Ángeles Muñoz-Fernández, María Ángeles Muñoz-Fernández, José Miguel Benito, José Miguel Benito, Salvador Resino, on Behalf of ECRIS Integrated in the Spanish AIDS Research Network   +16 more
doaj   +1 more source

Cancer biomarkers, and novel techniques for detection [PDF]

, 2017
Technologies for early detection of tumors is critical for better therapy outcome and overall change in cancer survival. These assays must be capable of detecting tumors at early stages in order to prevent metastasis of the tumor and help reduce ...
Jamal, Tameem
core  

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source