Results 121 to 130 of about 95,813 (295)

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

The Fermi Bubbles as Starburst Wind Termination Shocks

, 2014
The enhanced star formation in the inner 100 pc of the Galaxy launches a superwind at ~1600 km s$^{-1}$ for M82-like parameters. The ram pressure of the wind is very low compared to more powerful starburst winds. I show that halo gas stops the wind a few
Lacki, Brian C.
core   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Dynamics of First Order Transitions with Gravity Duals

, 2007
A first order phase transition usually proceeds by nucleating bubbles of the new phase which then rapidly expand. In confining gauge theories with a gravity dual, the deconfined phase is often described by a black hole.
E. Witten, G.T. Horowitz, Gary T Horowitz, H. Nastase, I.R. Klebanov, J. Kaplan, L. Randall, Matthew M Roberts, N.R. Constable, O. Aharony, P. Creminelli   +10 more
core   +3 more sources

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

Advanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess, Ellen F. Marsh, Veronica M. Lucian, Malavika Nair   +3 more
wiley   +1 more source

Scintillations in Southern Europe During the Geomagnetic Storm of June 2015

Remote Sensing
The sensitivity of Global Navigation Satellite System (GNSS) receivers to ionospheric disturbances and their constant growth are nowadays resulting in an increased concern of GNSS users about the impacts of ionospheric disturbances at mid-latitudes.
Anna Morozova, Luca Spogli, Teresa Barata, Rayan Imam, Emanuele Pica, Juan Andrés Cahuasquí, Mohammed Mainul Hoque, Norbert Jakowski, Daniela Estaço   +8 more
doaj   +1 more source

Hot bubbles of planetary nebulae with hydrogen-deficient winds - II. Analytical approximations with application to BD+30$^\circ$3639

, 2018
The first high-resolution X-ray spectroscopy of the planetary nebula BD+30$^\circ$3639 allowed to study X-ray emitting "hot bubbles" (HBs) of planetary nebulae in unprecedented detail.
Heller, René, Jacob, Ralf, Schönberner, Detlef, Steffen, Matthias   +3 more
core   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source